Exercise for Blood Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine how exercise and coaching can help older blood cancer survivors maintain health and slow aging. The study will compare two groups: one receiving supervised exercise sessions and coaching, and another with access to a virtual gym. Researchers seek to identify the optimal amount and duration of exercise needed to make a difference. This trial suits individuals over 50 who have had blood cancer and can safely engage in exercise activities. As a Phase 2 trial, it measures the treatment's effectiveness in an initial, smaller group, allowing participants to contribute to important research.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, it allows maintenance or lower-intensity chemotherapy for certain blood cancers, so you might be able to continue some treatments.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that exercise programs for cancer survivors are generally safe and manageable. One study found that supervised exercise reduced tiredness and improved quality of life without causing major issues. Another study confirmed that exercise can lower pain and breathing problems in cancer patients. Additionally, a large review found that exercise not only boosts well-being but also reduces the chance of negative events for people with cancer.
Regarding remote coaching, research suggests it works well after a supervised exercise program, helping cancer survivors maintain their fitness goals. Overall, these findings indicate that supervised exercise and coaching are safe options for improving health in cancer survivors.12345Why are researchers excited about this trial's treatments?
Researchers are excited about these treatments because they focus on exercise and lifestyle changes, which are not typical for blood cancer survivors. Most treatments for blood cancer involve chemotherapy, radiation, or targeted therapies, which can be tough on the body. The supervised exercise and coaching arm introduces a virtually monitored fitness routine combined with behavioral coaching to boost adherence, potentially enhancing recovery and quality of life. Meanwhile, the virtual gym membership offers a flexible, accessible way for survivors to stay active at their own pace. These approaches emphasize physical activity as a vital component of healing, offering a refreshing alternative to traditional medical interventions.
What evidence suggests that this trial's treatments could be effective for older blood cancer survivors?
Research has shown that exercise programs and coaching can greatly benefit cancer survivors. In this trial, participants in the Intervention Arm-Supervised will receive virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence. One study found that a six-month remote coaching program, following supervised exercise, increased physical activity in cancer survivors. Participants in the Enhanced Usual Care-Virtual Gym arm will have access to a virtual gym membership only. Another study demonstrated that a community exercise program improved physical health in just three months. Additionally, supervised exercise has been linked to better heart health and overall quality of life, including reduced body pain and fatigue. These findings suggest that structured exercise and coaching can effectively support the health and well-being of older blood cancer survivors.12678
Are You a Good Fit for This Trial?
This trial is for older adults who have survived different types of blood cancers, including various forms of leukemia, lymphoma, and myeloma. Participants should be interested in improving their health through exercise but currently do not meet physical activity recommendations.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in a virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Supervised Exercise and Coaching
- Virtual Gym Membership
Trial Overview
The HALTAging-1 Study is testing whether a program of supervised exercise and coaching or a virtual gym membership can slow down the biological aging process in older survivors of blood cancer. It's a Phase 2 study where participants are randomly assigned to one of the interventions.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
intervention arm incorporating virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
enhanced usual care arm, where survivors will get access to virtual gym membership only.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Nebraska
Lead Sponsor
Citations
Effects of remote coaching following supervised exercise ...
This study aimed to assess the effectiveness of a six-month remote coaching intervention, following a supervised exercise oncology rehabilitation program.
Effectiveness trial of a community-based supervised ...
Conclusions: A community-based exercise program of just 3 months in duration resulted in significant and sustained improvements in the physical, ...
3.
professional.heart.org
professional.heart.org/en/science-news/cardio-oncology-rehabilitation-to-manage-cardiovascular-outcomes-in-cancer-patients-and-survivors/CommentaryExercise-focused Rehabilitation for Cancer Survivors
The data for improved cardiovascular outcomes for individuals with cardiac disease participating in cardiac rehabilitation are clear10 and data for improved ...
Effect of supervised exercise training on objectively ...
This is the first randomized controlled trial on ET in patients with cancer that objectively tracked PA continuously over 6 months during and after AC therapy.
Community-based exercise program effectiveness and ...
Participants reported improvements in overall health-related quality of life (P< 0.001), social support (P=0.019), body pain (P=0.016), fatigue (P<0.001), ...
Supervised, structured and individualized exercise in ...
Our results indicate that the exercise intervention not only had a positive effect on physical fatigue and HRQOL but also on pain and dyspnea.
Impact of exercise on health outcomes in people with cancer
Conclusion Exercise reduces adverse events and enhances well-being through a range of health outcomes in people with cancer. Meta-analysis; Exercise; Randomised ...
Community-based exercise program effectiveness and safety ...
This investigation determined the effectiveness and safety of a disseminated community-based exercise program for cancer survivors who had completed treatment.
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