Milk Consumption for Metabolic Syndrome

Overseen By Eric Bruhn

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Mayo Clinic

Must not be taking: GLP-1 agonists, Steroids

Disqualifiers: Cardiovascular disease, Diabetes, Pregnancy, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 4

Duration: 8 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

The primary purpose of this study is to determine the impact of whole-fat dairy consumption on cardiovascular and metabolic risk factors and peripheral vascular function in adults with metabolic syndrome.

Who Is on the Research Team?

Joshua Smith, PhD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for adults with metabolic syndrome, characterized by low HDL cholesterol (below 40 mg/dL in men or 50 mg/dL in women), high triglycerides (150 mg/dL or above), elevated fasting glucose (100 mg/dL or above), large waist circumference (over 102 cm for men and 88 cm for women), and high blood pressure (130/80 mmHg or higher).

Inclusion Criteria

Presence of 3 of the following risk factors:

My blood pressure is high or I am on medication for it.

Waist circumference >102 cm for men and >88 cm for women

Exclusion Criteria

I am currently using a GLP-1 agonist medication.

My medication for metabolic syndrome will be adjusted during the study.

Dairy allergy or lactose intolerance

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume either a full-fat or low-fat dairy diet to assess impact on cardiovascular and metabolic risk factors

8 weeks

4 visits (in-person) at Baseline, Week 3, Week 5, and Week 8

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Full-fat diet
• Low-fat diet

Trial Overview

The study aims to compare the effects of a full-fat diet versus a low-fat diet on cardiovascular health, metabolism, and blood vessel function in individuals with metabolic syndrome.

How Is the Trial Designed?

Group I: Low-fat diet first then Full-fat diet Experimental Treatment 2 Interventions

Group II: Full-fat diet first then Low-fat diet Experimental Treatment 2 Interventions

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+