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Nap for Memory (HSR Trial)

Phase < 1
Research Sponsored by University of Maryland, College Park
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up across the nap period, approximately 2.5 hours
Awards & highlights


To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the researchers will assess memory, memory change over a nap and equivalent waking interval, sleep physiology of the nap, and brain structure and function (using Magnetic Resonance Imagining or MRI). Additionally, overnight sleep physiology will be assessed in all participants. Waves will take place approximately every 6 months. For all children, three waves will be collected. With these data, the researchers will address the following aims: Examine neural markers that predict the sleep transition (Aim 1); Examine changes in sleep-dependent memory processing (mnemonic discrimination) over both nap and overnight sleep intervals, across the sleep transition (Aim 2); Examine changes in sleep microstructure in both nap and overnight sleep across the sleep transition (Aim 3) Examine interrelations among brain, memory and sleep microstructure across the sleep transition (Aim 4)


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~across the nap period, approximately 2.5 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and across the nap period, approximately 2.5 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures

Trial Design

1Treatment groups
Experimental Treatment
Group I: NapExperimental Treatment1 Intervention
Children are nap promoted

Find a Location

Who is running the clinical trial?

University of Maryland, College ParkLead Sponsor
157 Previous Clinical Trials
46,072 Total Patients Enrolled
University of Massachusetts, AmherstOTHER
80 Previous Clinical Trials
467,972 Total Patients Enrolled
~120 spots leftby Jun 2028