80 Participants Needed

Contingency Management for Cannabis Use Disorder

(ACT Trial)

JA
KL
Overseen ByKatherine LeFevre, BS
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Indiana University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether brain scans can predict how well teens respond to a program aimed at reducing cannabis use. Participants will join 10 weekly virtual sessions to report their cannabis use and take home drug tests. Teens can earn prizes for staying cannabis-free. This program, called Contingency Management, is a behavioral therapy using positive reinforcement to encourage desired behaviors. It suits teens aged 14-17 who have used cannabis at least once a week in the past month and can undergo an MRI (a type of brain scan without any metal on or in the body). As an unphased trial, this study offers teens a unique opportunity to contribute to innovative research that could improve future treatment programs.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this treatment is safe for teens?

Research shows that contingency management is generally safe for teens with cannabis use disorder. This approach rewards positive actions, like staying drug-free, and can reduce cannabis use without harmful side effects. Studies on various treatments focusing on social and psychological aspects of cannabis use disorder have found them safe for similar groups.

Many studies have used contingency management, and participants usually handle it well. Tested in different locations, it has shown good results, with participants often reducing cannabis use. No specific reports of negative effects link to this treatment, suggesting it's a safe option for those considering joining the trial.12345

Why are researchers excited about this trial?

Researchers are excited about using Contingency Management for Cannabis Use Disorder because it offers a behavioral approach that rewards positive changes, unlike standard treatments that often rely on counseling and medication. This method uses incentives to encourage participants to reduce their cannabis use, which can be particularly effective for those who might not respond well to traditional therapies. Additionally, the integration of elastic net regression with neuroimaging data aims to provide personalized insights into treatment effectiveness, potentially paving the way for more tailored and effective intervention strategies.

What evidence suggests that Contingency Management is effective for Cannabis Use Disorder?

Research has shown that contingency management (CM) effectively helps people reduce cannabis use. In this trial, all participants will receive CM treatment for Cannabis Use Disorder. CM encourages drug-free behavior by offering rewards, such as prizes. Studies have found that CM results in more negative drug tests, indicating reduced cannabis use. Even after the rewards end, many continue to use less cannabis. This method has proven successful for both young people and adults, including those with mental health challenges.25678

Are You a Good Fit for This Trial?

This trial is for teens aged 14-17 who are trying to reduce their cannabis use. They'll need to participate in brain scans and attend virtual sessions for reporting usage and completing drug tests at home. Rewards are offered for staying cannabis-free.

Inclusion Criteria

I am between 14 and 17 years old.
Youth is MRI-eligible: No metal implants, prosthetics, orthodontic devices, transdermal medication patches, piercings and/or hair or eyelash extensions that cannot easily be removed, metallic ink tattoos on the neck or face, or claustrophobia, and are not pregnant
Youth must endorse having used cannabis at least once per week over the past month
See 1 more

Exclusion Criteria

Youth or caretaker who is monolingual non-English speaker
Youth who is currently undergoing contingency management treatment for cannabis use disorder
My child has a developmental, intellectual, or neurological condition.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (in-person)

Baseline Assessment

Participants undergo an fMRI scan and perform an instrumental learning task

1 week
1 visit (in-person)

Treatment

Participants engage in ten weekly virtual contingency management sessions

10 weeks
10 visits (virtual)

Follow-up

Participants are monitored for cannabis use disorder symptoms and readiness to change

1 week
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Contingency Management

Trial Overview

The study is examining if brain activity related to learning can predict the success of a treatment program aimed at decreasing cannabis use among adolescents through Contingency Management therapy.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Contingency Management and Elastic Net RegressionExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Indiana University

Lead Sponsor

Trials
1,063
Recruited
1,182,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

Contingency Management for Treatment of Cannabis Use ...

We found CM to be efficacious in producing cannabis use reductions and abstinence amongst individuals with a psychotic-spectrum or major depressive disorder.

Contingency Management for Cannabis Use Disorder ...

Results: Sixteen studies were included, and contingency management intervention likely promotes abstinence outcomes and more negative urinalyses ...

Contingency management is associated with positive ...

This study evaluated how short-duration contingency management (CM) impacts cannabis use attitudes and behavior after abstinence incentives are discontinued.

Do the benefits of providing motivational incentives used in ...

Contingency management is associated with positive changes in attitudes and reductions in cannabis use even after discontinuation of incentives among non- ...

Contingency Management: An Effective Strategy for Harm ...

This study was designed to assess the impact of contingency management (CM) on cannabis use attitudes and behaviors among non-treatment seeking ...

Contingency Management is Associated with Positive ...

This study evaluated how short-duration contingency management (CM) impacts cannabis use attitudes and behavior after abstinence incentives are discontinued.

Effectiveness and safety of psychosocial interventions for ...

Aim To evaluate the effectiveness, safety and cost-effectiveness of psychosocial interventions for cannabis use disorder (CUD).

Disparities in Treatment Outcomes for Cannabis Use ...

This study examined treatment outcomes for cannabis use disorder (CUD) among adolescents (12–17 years old) in the United States.