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Brain Metabolism of Sensory Signals in Healthy Subjects

N/A
Waitlist Available
Led By Christin Y Sander, PhD
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after pet image analysis and with study completion, an average of 1 year
Awards & highlights

Study Summary

This trial will explore how the brain uses energy to process sensory signals, using cutting-edge imaging tech.

Who is the study for?
This trial is for right-handed, English-speaking adults aged 21-35 with no MRI or PET scan contraindications. Excluded are those with kidney/liver issues, severe past COVID-19, major head trauma, certain chronic conditions, smokers, BMI over 35, and those who can't consent or lie still in a scanner.Check my eligibility
What is being tested?
The study uses hybrid PET/fMRI imaging to observe how the brain's glucose and oxygen metabolism responds to unpredictable sensory signals. It aims to understand the metabolic processes during such cognitive tasks.See study design
What are the potential side effects?
Since this trial involves non-invasive imaging techniques rather than drugs or medical interventions, side effects are minimal but may include discomfort from lying still and potential claustrophobia in the scanning machines.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after pet image analysis and with study completion, an average of 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and after pet image analysis and with study completion, an average of 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Brain positron emission tomography (PET) imaging signals
Functional magnetic resonance imaging (fMRI) signals
Oxygen-glucose index

Trial Design

1Treatment groups
Experimental Treatment
Group I: Behavioral interventionExperimental Treatment1 Intervention
Subjects are presented with a simultaneous sequence of faces and spoken words. Face stimuli include a representative sample of realistic faces across a range of ages. Spoken word stimuli are simple nouns spoken by a single female speaker.

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,928 Previous Clinical Trials
13,198,325 Total Patients Enrolled
Christin Y Sander, PhDPrincipal InvestigatorAthinoula A. Martinos Center for Biomedical Imaging
1 Previous Clinical Trials
30 Total Patients Enrolled

Media Library

Behavioral intervention Clinical Trial Eligibility Overview. Trial Name: NCT05756335 — N/A
Healthy Subjects Research Study Groups: Behavioral intervention
Healthy Subjects Clinical Trial 2023: Behavioral intervention Highlights & Side Effects. Trial Name: NCT05756335 — N/A
Behavioral intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT05756335 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still available openings for this research endeavor?

"The information on clinicaltrials.gov shows that this particular medical trial is not currently accepting new admission applications. This study was first published on March 1st 2023 and its most recent update occurred February 23rd of the same year. Nonetheless, 819 other studies are actively recruiting patients at present."

Answered by AI

Are there certain demographics that are particularly suitable for participating in this trial?

"To be eligible for this trial, potential candidates must have optimal health and fall within the 21 to 35 age range. A total of 30 participants are being recruited."

Answered by AI

Are participants of an advanced age invited to take part in this medical test?

"To qualify for this trial, applicants must be between the ages of 21 and 35. For those younger than 18 or older than 65 there are 51 studies available to them respectively."

Answered by AI

Who else is applying?

What site did they apply to?
Athinoula A. Martinos Center for Biomedical Imaging
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
The Brain Metabolism of Unpredictable Signals
Christin Y. Sander, PhD 2023. "The Brain Metabolism of Unpredictable Signals". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05756335.
~14 spots leftby Apr 2025
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