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Surgical Interventions for Cervical Cancer

N/A
Waitlist Available
Led By Allan L Covens
Research Sponsored by Gynecologic Oncology Group
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 years
Awards & highlights

Study Summary

This trial looks at how surgery for early-stage cervical cancer affects patients' quality of life.

Eligible Conditions
  • Lymphedema
  • Cervical Cancer
  • Cervical Adenocarcinoma
  • Cervical Carcinoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in bladder and bowel function score based on supplemental bladder and bowel questions plus 4 items from the Functional Assessment of Cancer Therapy-Cervix (3 bladder and 1 bowel question)
Change in sexual function and activity based on Female Sexual Function Index (19 items) score plus 2 Patient Reported Outcomes Measurement Information System screener items
Lymphedema
+1 more
Secondary outcome measures
Change in cancer worries based on Impact of Events score
Change in overall quality of life
Change in reproductive concerns based on reproductive concerns (14 items) score
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Treatment (cone biopsy/lymphadenectomy or hysterectomy)Experimental Treatment5 Interventions
Patients undergo cone biopsy and pelvic lymphadenectomy or simple hysterectomy and pelvic lymphadenectomy.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Conization
1998
N/A
~690
Therapeutic Conventional Surgery
2005
Completed Phase 3
~9850

Find a Location

Who is running the clinical trial?

Gynecologic Oncology GroupLead Sponsor
250 Previous Clinical Trials
70,702 Total Patients Enrolled
4 Trials studying Lymphedema
1,177 Patients Enrolled for Lymphedema
GOG FoundationLead Sponsor
41 Previous Clinical Trials
15,917 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,932,929 Total Patients Enrolled
31 Trials studying Lymphedema
14,106 Patients Enrolled for Lymphedema

Media Library

Therapeutic Conventional Surgery Clinical Trial Eligibility Overview. Trial Name: NCT01649089 — N/A
Lymphedema Research Study Groups: Treatment (cone biopsy/lymphadenectomy or hysterectomy)
Lymphedema Clinical Trial 2023: Therapeutic Conventional Surgery Highlights & Side Effects. Trial Name: NCT01649089 — N/A
Therapeutic Conventional Surgery 2023 Treatment Timeline for Medical Study. Trial Name: NCT01649089 — N/A
Lymphedema Patient Testimony for trial: Trial Name: NCT01649089 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What aims does this clinical trial endeavor to meet?

"This research will measure the effectiveness of a non-radical surgical procedure by evaluating changes in bladder and bowel function scores, recurrence-free survival rates, overall quality of life as defined by Functional Assessment of Cancer Therapy-Cervix (15 items) score, and maximum grade of treatment related adverse events graded according to Common Terminology Criteria for Adverse Events version 4.0 or 5.0 depending on when the trial commenced. This assessment will take place over roughly three years following the surgery with Kaplan–Meier product limit estimates used to determine recurrence free survival while Cox regression will be employed to calculate hazard ratios controlling for known prog"

Answered by AI

Is there still availability for participants in this experiment?

"Contrary to expectations, clinicaltrials.gov affirms that this experiment is not currently recruiting participants; a process that began on October 1st 2012 and was last modified near the end of 2022. Fortunately, there are many other trials actively sourcing patients at present with 2943 options available."

Answered by AI

How many locations are participating in the implementation of this trial?

"To participate in this research trial, prospective patients can visit Dublin Methodist Hospital in Dublin, Oklahoma, Genesis Healthcare System Cancer Care Center in Zanesville, Rhode island or OhioHealth Mansfield Hospital in Mansfield California among 41 other sites."

Answered by AI

Who else is applying?

How old are they?
18 - 65
What site did they apply to?
Dana-Farber Cancer Institute
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
What state do they live in?
Virginia
California
How many prior treatments have patients received?
0
2

Why did patients apply to this trial?

I have a wish for medicine that can help control the swelling of lymphedema in one full leg.
PatientReceived no prior treatments
I Would like this clinic al trial could help cancer survivors to leave best without lymphedema if possibile.
PatientReceived no prior treatments

What questions have other patients asked about this trial?

Can this be done remotely?
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
2012. "Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01649089.
All > Cervical Cancer
~18 spots leftby Apr 2025
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