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Radiation Therapy

Radiation Schedules for Early-Stage Lung Cancer

N/A

Recruiting

Research Sponsored by University of Rochester

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients with hilar or mediastinal lymph nodes ≤ 1cm and no abnormal hilar or mediastinal uptake on PET will be considered N0

Patients with primary non-small cell lung cancers of the following types: squamous cell carcinoma, adenocarcinoma, large cell carcinoma, bronchioalveolar cell carcinoma, or non-small cell carcinoma not otherwise specified

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

Study Summary

This trial is looking at whether people have different side effects from radiation depending on how often they have it.

Who is the study for?

This trial is for adults with early-stage non-small cell lung cancer, specifically certain types of squamous cell carcinoma, adenocarcinoma, and others without spread to lymph nodes or other organs. Participants should be in fair health and not pregnant. They must agree to use contraception and have no recent history of other cancers or prior chest radiation.Check my eligibility

What is being tested?

The study compares two schedules of radiation therapy for treating lung cancer: one group will receive three fractions (doses) while the other gets five fractions. The aim is to see if side effects differ between these two treatment schedules.See study design

What are the potential side effects?

Radiation therapy can cause skin irritation at the treatment site, fatigue, shortness of breath, coughing, and may affect normal lung tissue leading to inflammation known as pneumonitis.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My lymph nodes in the chest area are normal size and show no signs of cancer on a PET scan.

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My lung cancer is one of the specified types (e.g., squamous, adenocarcinoma).

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My cancer is early stage, not spread to lymph nodes or other parts.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

frequency of grade 3 treatment related toxicities or higher

Secondary outcome measures

mean survival time of patients with overall survival

proportion of patients with disease-free survival

proportions of patients with primary tumor control

Trial Design

2Treatment groups

Active Control

Group I: Stereotactic body radiotherapy- 3 fractionsActive Control1 Intervention

Group II: Stereotactic body radiotherapy- 5 fractionsActive Control1 Intervention

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of RochesterLead Sponsor

840 Previous Clinical Trials

534,150 Total Patients Enrolled

Media Library

$Radiation therapy-3 fractions (Radiation Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT03706027 — N/A$

$Lung Cancer Research Study Groups: Stereotactic body radiotherapy- 3 fractions, Stereotactic body radiotherapy- 5 fractions$

$Lung Cancer Clinical Trial 2023: Radiation therapy-3 fractions Highlights & Side Effects. Trial Name: NCT03706027 — N/A$

$Radiation therapy-3 fractions (Radiation Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03706027 — N/A$

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical trial looking for new participants?

"The listed clinical trial on clinicaltrials.gov is recruiting patients. The trial was first posted on December 15th, 2018 and was most recently updated on August 5th, 2021."

Answered by AI

What is the quota for participants in this experiment?

"That is correct. If you consult clinicaltrials.gov, you will see that the trial in question has been actively recruiting since December 15th, 2018. The 100 participants are needed at a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer

Deepinder P Singh, MD 2018. "Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03706027.