Radiofrequency Ablation for Chronic Knee Pain
(RACKTKA Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you stop taking anticoagulants (blood thinners) for three days before the procedure, with approval from your doctor. Other medications are not specifically mentioned, so it's best to discuss with the study team.
What data supports the effectiveness of the treatment Genicular Nerve Radiofrequency Ablation for chronic knee pain?
Is radiofrequency ablation for chronic knee pain safe?
How is genicular nerve radiofrequency ablation different from other treatments for chronic knee pain?
What is the purpose of this trial?
The purpose of this study is to assess how clinically useful and safe genicular nerve radiofrequency ablation is in people with chronic pain after total knee arthroplasty performed for osteoarthritis.
Research Team
Timothy E McAlindon, MD, MPH
Principal Investigator
UMass Worcester (UMass Chan Medical School)
Phibi E Ngankam, BS
Principal Investigator
UMass Worcester (UMass Chan Medical School)
Eligibility Criteria
This trial is for adults over 18 who've had knee replacement surgery at least a year ago and are in good health except for chronic knee pain. They must find their current state unacceptable, be willing to track pain daily, and not be on anticoagulants or pregnant. Those with infection in the knee or loose prosthesis, exclusive posterior knee pain, or less than 70% pain reduction after a test block can't join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo genicular nerve radiofrequency ablation or sham procedure
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Genicular Nerve Radiofrequency Ablation
- Sham
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Massachusetts, Worcester
Lead Sponsor
Tufts Medical Center
Collaborator
Boston University
Collaborator
Rheumatology Research Foundation
Collaborator