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Diagnostic Test

Quick Renal MRI for Pediatric Kidney Disease

N/A
Recruiting
Led By Ruthie Su, MD
Research Sponsored by University of Wisconsin, Madison
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis undergoing clinical DMSA scan
History of more than one UTI in the past year
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 6 months
Awards & highlights

Study Summary

This trial proposes a new, faster imaging technique for children with urinary tract problems that is injection-, sedation-, and radiation-free. It could potentially replace current scans and ease the burden of testing for kids with chronic renal disease.

Who is the study for?
This trial is for children and young adults (0-21 years) with kidney conditions like infections or scarring, who are already getting DMSA scans as part of their care. It's not for those uncomfortable with MRI, without signs of infection in urine tests, negative urine cultures, or who can't have an MRI due to other medical reasons.Check my eligibility
What is being tested?
The study is testing a new 'quick renal MRI' method against the standard DMSA scan used to detect kidney infections and scarring. The goal is to see if this quick MRI can be a faster, safer option that doesn't need injections, sedation, or radiation.See study design
What are the potential side effects?
Since the quick renal MRI does not use radiation, sedation, or injections unlike traditional imaging methods such as the DMSA scan; it's expected to have fewer risks. However specific side effects aren't listed since MRIs typically don’t involve any.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am in the hospital for a fever and kidney infection, getting a special kidney scan.
Select...
I have had more than one urinary tract infection in the last year.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Sensitivity of Quick MRI as Compared to DMSA scan in Diagnosis of Suspected Acute Pyelonephritis
Sensitivity of Quick MRI as compared to DMSA scan in Diagnosis of Renal Scars
Specificity of Quick MRI as compared to DMSA scan in Diagnosis of Renal Scars

Trial Design

1Treatment groups
Experimental Treatment
Group I: DMSA/Quick MRIExperimental Treatment1 Intervention
All participants will go through DMSA and Quick MRI scan to help determine the validity of the Quick Renal MRI in pediatric kidney disease.

Find a Location

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,190 Previous Clinical Trials
3,169,527 Total Patients Enrolled
Ruthie Su, MDPrincipal InvestigatorUniversity of Wisconsin, Madison
Shannon Cannon, MDPrincipal InvestigatorUniversity of Wisconsin, Madison

Media Library

Quick MRI (Diagnostic Test) Clinical Trial Eligibility Overview. Trial Name: NCT03959163 — N/A
Acute Pyelonephritis Research Study Groups: DMSA/Quick MRI
Acute Pyelonephritis Clinical Trial 2023: Quick MRI Highlights & Side Effects. Trial Name: NCT03959163 — N/A
Quick MRI (Diagnostic Test) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03959163 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Developmental Medicine & Child NeurologyJournal
Expectation of Life and Unexpected Death in Open Spina Bifida: A 40-year Complete, Non-selective, Longitudinal Cohort Study
OAKESHOTT, PIPPA, GILLIAN M HUNT, ALISON POULTON, and FIONA REID. 2009. “Expectation of Life and Unexpected Death in Open Spina Bifida: A 40-year Complete, Non-selective, Longitudinal Cohort Study”. Developmental Medicine & Child Neurology. Wiley. doi:10.1111/j.1469-8749.2009.03543.x.
clinicaltrials.govStudy
The Validity of the Quick Renal MRI in Pediatric Kidney Disease
2019. "The Validity of the Quick Renal MRI in Pediatric Kidney Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03959163.
All > Kidney Failure
~10 spots leftby Jan 2025
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