Iron Supplements for Iron-Deficiency Anemia
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial compares different iron supplements to determine which best boosts hemoglobin levels in individuals with iron-deficiency anemia. It evaluates Ferrous Ascorbate, Ferrous Fumarate, and Polysaccharide Iron to identify which is more effective and easier to tolerate. This trial suits those diagnosed with iron-deficiency anemia who are not currently taking iron supplements. Participants must be willing to discontinue any current iron treatments during the study. As an unphased trial, it offers a unique opportunity to contribute to valuable research that could enhance future treatment options for iron-deficiency anemia.
Do I have to stop taking my current medications for the trial?
Yes, if you are currently taking an iron supplement, you must stop it when you sign the consent form and throughout the study. Additionally, you cannot take certain other medications like Proton Pump Inhibitors or multivitamins with high iron content during the trial.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that ferrous fumarate is generally safe for treating iron deficiency, including for pregnant women. However, excessive intake can lead to serious iron poisoning, so following the recommended doses is crucial.
Ferrous ascorbate is also well-tolerated and often used for mild to moderate iron deficiency anemia. The body easily absorbs it, and it has no major food interactions, making it simple to include in a daily routine.
Studies have shown that polysaccharide iron, such as FeraMAX, is safe and has a safety profile similar to other iron treatments. However, individuals with certain conditions, like hemochromatosis (where the body absorbs too much iron), should avoid it.
Overall, research indicates that these iron supplements are safe when used correctly. Always adhere to the provided guidelines to avoid any side effects.12345Why are researchers excited about this trial's treatments?
Researchers are excited about these treatments for iron-deficiency anemia because they offer unique formulations that might improve iron absorption and reduce side effects compared to standard options like ferrous sulfate. Ferrous Ascorbate (EBMfer) combines iron with ascorbic acid, which can enhance iron absorption in the body. Ferrous Fumarate (Eurofer) is another form of iron that is well-absorbed and may be easier on the stomach for some patients. Polysaccharide Iron (FeraMAX) features a different delivery method that encapsulates iron in a complex carbohydrate, potentially reducing gastrointestinal irritation. Each of these treatments provides a fresh approach to managing iron levels more effectively and comfortably.
What evidence suggests that this trial's treatments could be effective for iron-deficiency anemia?
This trial will compare different iron supplements for treating iron-deficiency anemia (IDA). Research has shown that ferrous ascorbate, which participants may receive, effectively increases hemoglobin levels. Studies indicate it can significantly raise hemoglobin levels compared to other iron supplements. Ferrous fumarate, another treatment option in this trial, has also demonstrated strong results, with notable improvements in hemoglobin and ferritin levels after 90 days. Additionally, polysaccharide iron, also tested in this trial, has proven effective, with results showing up to 99% improvement in maintaining iron levels. All these treatments are good options for managing IDA.13467
Are You a Good Fit for This Trial?
This trial is for adults aged 18 or older who are dealing with iron deficiency anemia. Participants should have a confirmed diagnosis of IDA and be willing to take oral iron supplements. Specific details about what might exclude someone from participating aren't provided, but typically these criteria would involve health conditions that could interfere with the study or risk participant safety.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive oral treatment with either Ferrous Ascorbate, Ferrous Fumarate, or Polysaccharide Iron for 12 weeks to assess changes in hemoglobin levels
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Ferrous Ascorbate
- Ferrous Fumarate
- Polysaccharide Iron
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dr. Anil K. Gupta Medicine Professional Corporation
Lead Sponsor