40 Participants Needed

Developmental Impacts of Microplastics Exposure in Early Life

(DIMPLE Trial)

Recruiting at 1 trial location
TL
CH
Overseen ByCharlotte Haslett
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Colorado, Boulder
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothers and infants in mother-infant dyads 1 or 3 months postpartum living in Baltimore, Maryland. The main questions it aims to answer are: * What MNPs are present in breastmilk and maternal blood samples and in their infants stool sample? * Are there associations between amount of maternal MNPs in breast milk and mass of MNP particles in infant stool? * Which environmental and lifestyle factors are most predictive of maternal MNP burden? * Is infant exposure to MNPs associated with birth weight and postnatal growth trajectories? Participants will: * Complete several questionnaires assessing medical histories, lifestyle factors, environmental exposures, eating behaviors, etc. * Provide biological specimens including: maternal blood, stool, and breastmilk; infant stool * Clinical visit to have anthropometric measures documented including maternal height and weight, infant weight, length, and skin-fold thickness

Research Team

TL

Tanya L Alderete, PhD

Principal Investigator

Johns Hopkins Bloomberg School of Public Health

Eligibility Criteria

Inclusion Criteria

You identify with any gender identity or expression.
You have never given birth to a single child.
You are a mother who has given birth within the past four weeks or so.
See 1 more

Treatment Details

Participant Groups
2Treatment groups
Experimental Treatment
Group I: County Mother-Infant PairsExperimental Treatment1 Intervention
Mother-infant pairs living in a Baltimore County, Maryland zip code exposed to micro and nano plastics.
Group II: City Mother-Infant PairsExperimental Treatment1 Intervention
Mother-infant pairs living in a Baltimore City, Maryland zip code exposed to micro and nano plastics.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Colorado, Boulder

Lead Sponsor

Trials
128
Recruited
29,600+

Johns Hopkins Bloomberg School of Public Health

Lead Sponsor

Trials
441
Recruited
2,157,000+

Sonoma Technology, Inc.

Collaborator

Trials
1
Recruited
40+

Emory University

Collaborator

Trials
1,735
Recruited
2,605,000+