Developmental Impacts of Microplastics Exposure in Early Life
(DIMPLE Trial)
Trial Summary
What is the purpose of this trial?
The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothers and infants in mother-infant dyads 1 or 3 months postpartum living in Baltimore, Maryland. The main questions it aims to answer are: * What MNPs are present in breastmilk and maternal blood samples and in their infants stool sample? * Are there associations between amount of maternal MNPs in breast milk and mass of MNP particles in infant stool? * Which environmental and lifestyle factors are most predictive of maternal MNP burden? * Is infant exposure to MNPs associated with birth weight and postnatal growth trajectories? Participants will: * Complete several questionnaires assessing medical histories, lifestyle factors, environmental exposures, eating behaviors, etc. * Provide biological specimens including: maternal blood, stool, and breastmilk; infant stool * Clinical visit to have anthropometric measures documented including maternal height and weight, infant weight, length, and skin-fold thickness
Research Team
Tanya L Alderete, PhD
Principal Investigator
Johns Hopkins Bloomberg School of Public Health
Eligibility Criteria
Inclusion Criteria
Treatment Details
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Who Is Running the Clinical Trial?
University of Colorado, Boulder
Lead Sponsor
Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
Sonoma Technology, Inc.
Collaborator
Emory University
Collaborator