Ice Therapy for Injection Site Pain
Trial Summary
What is the purpose of this trial?
Purpose: To examine the difference in patient's pain experience in the setting of intravitreal anti-VEGF injections with pretreatment of topical ice-therapy compared with no-ice.
Do I need to stop my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Ice-therapy for reducing injection site pain?
Is ice therapy safe for reducing pain at injection sites?
How does ice therapy differ from other treatments for injection site pain?
Ice therapy is unique because it uses cold to numb the skin and reduce pain at the injection site, which is different from traditional methods like topical anesthetics that can have a longer duration and unpleasant taste. This method is simple, safe, and effective, especially for children and anxious patients.2371011
Research Team
Jade Moon, MD
Principal Investigator
University of Minnesota
Eligibility Criteria
This trial is for adults 18 or older who need an anti-VEGF intravitreal injection for eye conditions, as determined by a retina specialist at the University of Minnesota Department of Ophthalmology. There are no specific exclusion criteria listed.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive intravitreal anti-VEGF injections with or without pretreatment of topical ice-therapy
Follow-up
Participants are monitored for pain, discomfort, burning, itching, and overall tolerability 24 hours after the injection
Treatment Details
Interventions
- Ice-therapy
- No Ice-therapy
Ice-therapy is already approved in United States, European Union, Canada for the following indications:
- Pain management for intravitreal injections
- Pain relief for ocular procedures
- Local anesthesia for intravitreal injections
- Pain management for eye injections
- Anesthesia for minor ocular surgeries
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Minnesota
Lead Sponsor