High Intensity Interval Training for Hodgkin's Lymphoma Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores the feasibility of a 12-week high-intensity interval training (HIIT) program for individuals who survived Hodgkin's lymphoma in their youth. The goal is to determine if HIIT can improve fitness, body health, and overall physical activity after treatment. It is ideal for those who had Hodgkin's lymphoma, completed treatment within the last two years, and are ready for physical exercise. Participants will engage in 25-minute HIIT sessions three times a week, each including warm-ups and cool-downs. The trial seeks survivors who are not currently engaged in intense workouts or excessive exercise.
As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance post-treatment recovery and fitness.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this high intensity interval training program is safe for Hodgkin's lymphoma survivors?
Research shows that high-intensity interval training (HIIT) is generally safe for cancer survivors. Studies indicate that people who have undergone cancer treatment can perform HIIT with few or no negative effects. This exercise involves short bursts of intense activity followed by brief rest periods. Previous trials found that cancer survivors usually handle these workouts well, with few reports of side effects. This suggests that the HIIT program in this trial is likely safe for Hodgkin's lymphoma survivors.12345
Why are researchers excited about this trial?
Researchers are excited about using High Intensity Interval Training (HIIT) for Hodgkin's Lymphoma survivors because it offers a non-pharmacological approach to improving health and fitness. Unlike standard treatments for Hodgkin's Lymphoma, which often include chemotherapy and radiation, HIIT focuses on enhancing cardiovascular health and physical strength without additional medication. The high-intensity, short-duration workouts are designed to maximize heart health and recovery, potentially leading to improved quality of life for survivors. This exercise regimen is unique in its ability to target fitness levels quickly, with sessions lasting just 25 minutes, making it an efficient option for those looking to regain their strength post-treatment.
What evidence suggests that high intensity interval training is effective for Hodgkin's lymphoma survivors?
Research has shown that High Intensity Interval Training (HIIT) benefits cancer survivors, including those with Hodgkin's lymphoma. Studies have found that HIIT can enhance quality of life and physical fitness. For instance, cancer patients in a HIIT program reported improved quality of life. Participation rates in these programs range from 54% to 100%. In this trial, participants in the HIIT Intervention Group will complete a 12-week HIIT program. Overall, HIIT appears promising for helping Hodgkin's lymphoma survivors improve their physical health and well-being.12367
Who Is on the Research Team?
Amy Berkman, MD
Principal Investigator
St. Jude Children's Research Hospital
Are You a Good Fit for This Trial?
This trial is for survivors of childhood, adolescent, and young adult Hodgkin lymphoma who finished treatment within the last 24 months. It's designed to see if they can participate in a high-intensity exercise program.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo baseline assessments including exercise testing, body composition, autonomic function, and blood biomarkers
Treatment
Participants complete a 12-week HIIT program with three 25-minute sessions per week, delivered via a secure web-based platform with live supervision
Post-intervention Assessment
Participants undergo post-intervention assessments to evaluate changes in health outcomes
Follow-up
Participants are monitored for safety and effectiveness after the intervention
What Are the Treatments Tested in This Trial?
Interventions
- High Intensity Interval Training (HIIT)
Trial Overview
The study tests a 12-week High Intensity Interval Training (HIIT) program. It aims to check how feasible it is for participants and measure its effects on fitness, body composition, physical function, response to exercise, nerve health, aging markers, and activity levels.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants will complete a 12-week HIIT program with three 25-minute sessions per week. Each session includes warm-up, five cycles of high-intensity intervals (80-95% peak HR) and recovery periods (50-60% peak HR), and cool-down.
Find a Clinic Near You
Who Is Running the Clinical Trial?
St. Jude Children's Research Hospital
Lead Sponsor
Citations
Feasibility of High Intensity Interval Training in Survivors ...
This pilot study evaluates the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, ...
Effectiveness of HIIT in Cancer Patients & Survivors: Review
QoL showed positive results although with some controversy. Adherence to HIIT intervention was high, ranging from 54% to 100%.
3.
ctv.veeva.com
ctv.veeva.com/study/feasibility-of-high-intensity-interval-training-in-survivors-of-childhood-adolescent-and-young-aduFeasibility of High Intensity Interval Training in Survivors of ...
This pilot study evaluates the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, ...
High Intensity Interval Training for Hodgkin's Lymphoma ...
This pilot study evaluates the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, ...
Effects of HIIT on Quality of Life in CLL: Pilot Study
Scores for FWB improved following HIIT+RT (21.7 ± 3.4 to 23.9 ± 3.2; ES = 1.38) compared to controls (25.7 ± 2.2 to 25.7 ± 2.3). The HIIT+RT group experienced ...
The impact of high intensity interval training in a diverse ...
We observed meaningful improvements in body composition, HbA1c and quality of life over 12 weeks among cancer survivors participating in a high-intensity ...
Effects of high-intensity interval training on health-related ...
The purpose of this study was to investigate the effects of a 12-week HIIT and RT (HIIT+RT) intervention on HRQOL in adults with treatment naïve CLL.
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