Skin Patch Monitor for Gout
Trial Summary
What is the purpose of this trial?
15 patients with gout \[10 patients no recent urate-lowering therapy (ULT) and 5 patients on stable urate-lowering therapy (ULT)\] will be invited to participate in a standardized meal at the UCLA Human Nutrition Center and a 7-day community follow-up for the measurement of uric acid (and other metabolites) using our Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does mention that 5 participants should be on stable urate-lowering therapy without any dose changes in the last 30 days. If you are on urate-lowering therapy, you may need to continue it without changes.
What data supports the effectiveness of the UR+AIMS skin patch treatment for gout?
The research on wearable sensor patches with hydrogel microneedles shows that such patches can effectively monitor biomarkers in interstitial fluid, which is important for managing chronic conditions. This suggests that the UR+AIMS skin patch might also be effective in monitoring and managing gout by tracking relevant biomarkers.12345
What safety information is available for skin patch monitors like the UR+AIMS skin patch?
How does the Skin Patch Monitor for Gout treatment differ from other treatments for gout?
The Skin Patch Monitor for Gout is unique because it uses a wearable microneedle patch to monitor uric acid levels in a minimally invasive way, allowing patients to see changes in uric acid levels with the naked eye. This approach is different from traditional blood tests and offers real-time monitoring, which can improve patient compliance and convenience.1112131415
Research Team
John FitzGerald, MD
Principal Investigator
University of California, Los Angeles
Eligibility Criteria
This trial is for 15 people with gout, some of whom haven't had recent urate-lowering therapy and others who are on a stable urate-lowering regimen. Participants will join a meal study at UCLA and then wear a skin patch that monitors uric acid levels for a week.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Initial Visit and Meal Test
Participants sign consent, complete questionnaires, and undergo a standardized meal test with blood draws at the UCLA Human Nutrition Center
Community 7-day Observation
Participants apply the study patch daily and record various health metrics using the study mobile device
Follow-up
Participants are monitored for safety and effectiveness after the observation period
Treatment Details
Interventions
- UR+AIMS skin patch
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Los Angeles
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator