Prism Glasses for Visual Field Loss

Overseen By Sailaja Manda

Age: Any Age

Sex: Any

Trial Phase: Academic

Sponsor: Massachusetts Eye and Ear Infirmary

Disqualifiers: Cognitive dysfunction, Balance problems, Seizures, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 4

Duration: 4 months

20 Participants Needed

Trial Summary

What is the purpose of this trial?

The investigators will develop and test different configurations of high-power prisms to expand the field of vision of patients with visual field loss to assist them with obstacle detection when walking. The study will involve multiple visits (typically four) to Schepens Eye Research Institute for fitting and testing with the prism glasses. The overall objective is to determine best designs and fitting parameters for implementation in prism devices for future clinical trials.

Research Team

Eliezer Peli, MSc, OD

Principal Investigator

Schepens Eye Research Institute of Massachusetts Eye and Ear

Eligibility Criteria

This trial is for people with certain types of visual field loss, like tunnel vision or hemianopia. Participants must have at least 20/50 vision in their better eye, be able to walk on their own, speak English, and complete sessions up to 4 hours. It's not for those with recent seizures, balance issues that affect walking, cognitive problems, or hemispatial neglect.

Inclusion Criteria

I can complete activities lasting 2-4 hours without major issues.

You must be able to see at least 20/50 in your better eye.

I can walk on my own for short distances.

Exclusion Criteria

I do not have any physical or mental conditions that would stop me from walking or using special glasses.

I have had a seizure in the past 6 months.

I have difficulty noticing things on one side of my body.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are fitted with various configurations of high-power prisms and tested for visual field expansion and obstacle detection

4 months

4 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• High power prisms

Trial Overview The study tests various high-power prism configurations designed to widen the visual field and help detect obstacles while walking. Participants will visit Schepens Eye Research Institute multiple times for fitting/testing these new prism glasses to find the best designs for future use.

Participant Groups

Group I: High power prisms Experimental Treatment 1 Intervention

Various configurations of high power prisms will be developed for each individual and custom fit into spectacles lenses.

Who Is Running the Clinical Trial?

Massachusetts Eye and Ear Infirmary

Lead Sponsor

Trials

115

Recruited

15,000+

National Eye Institute (NEI)

Collaborator

Trials

572

Recruited

1,320,000+