Psychosocial Intervention for Bone Marrow Transplant
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores ways to help patients and their family caregivers manage the medical routine after a stem cell transplant. It tests two approaches: Dyadic Problem Solving Training, which teaches problem-solving skills, and supportive care. The goal is to determine if these methods can improve emotional coping and health task management for patients and caregivers. It suits those scheduled for a stem cell transplant at the University of Pittsburgh Hillman Cancer Center with a family caregiver willing to participate. As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance support for future patients and caregivers.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that these psychosocial interventions are safe?
Research has shown that Dyadic Problem Solving Training (DPST) is safe for both patients and caregivers. Studies have found that similar training during stem cell transplants is feasible and well-received. Participants have found these programs helpful and engaging, with no major safety issues reported.
Supportive Care, the other treatment under evaluation, typically provides emotional and practical assistance. This common method has a strong safety record and is considered safe for patients and caregivers managing medical treatments. Both treatments focus on non-invasive support, making them low-risk and safe options for participants.12345Why are researchers excited about this trial?
Researchers are excited about these interventions because they focus on the psychosocial aspects of bone marrow transplant care, which is often overlooked in standard medical treatments. Dyadic Problem Solving Training (DPST) is unique because it actively teaches both patients and their caregivers problem-solving skills to manage the demanding medical regimen together, fostering a collaborative approach. On the other hand, Supportive Care offers emotional and practical support to help both parties navigate the challenges of the transplant process. These interventions aim to enhance the overall well-being of patients and caregivers, potentially improving treatment outcomes and quality of life.
What evidence suggests that this trial's psychosocial interventions could be effective for improving adherence to the medical regimen after stem cell transplant?
This trial will compare two approaches: Dyadic Problem Solving Training (DPST) and Supportive Care. Research has shown that DPST can help patients and caregivers manage medical care after a bone marrow transplant. Studies have found that DPST aids in problem-solving, reducing stress and improving coping during difficult times. Caregivers of children undergoing similar treatments experienced less distress after problem-solving training. Meanwhile, Supportive Care, another approach in this trial, focuses on providing emotional support, helping patients and caregivers feel more connected and less isolated. Both approaches have shown promise in assisting people in handling the challenges of medical care after a transplant.12467
Are You a Good Fit for This Trial?
This trial is for patients scheduled for a stem cell transplant at the University of Pittsburgh Hillman Cancer Center, who are 18 or older and have a family caregiver aged 18+ willing to join the study. Participants must be English speakers without a previous stem cell transplant.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants and family caregivers undergo a 4-session psychosocial intervention via live video conferencing
Follow-up
Participants are monitored for psychosocial and health-related outcomes post-intervention
What Are the Treatments Tested in This Trial?
Interventions
- Dyadic Problem Solving Training
- Supportive Care
Trial Overview
The study tests two psychosocial interventions: Supportive Care and Dyadic Problem Solving Training, to see if they help with adherence to medical regimens post-transplant and improve overall well-being of patients and their caregivers.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
DPST will teach problem solving skills to both the patient and family caregiver as they manage the medical regimen.
Supportive Care will provide support to both the patient and family caregiver as they manage the medical regimen.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
Citations
An Individualized Dyadic Problem-Solving Education ...
Results suggest that dyads can participate in PSE during HSCT and view it as beneficial. Participants identified the active process of solving problems as ...
Problem-Solving Skills Training for Parents of Children ...
Overall, the study results suggest that Bright IDEAS® is a promising way to help caregivers during their child's HSCT, and it may decrease symptoms of distress, ...
Hematopoietic Cell Transplantation Patient-Caregiver ...
The purpose of this qualitative descriptive study was to explore participants' perceptions of a 4-week web-based digital storytelling (DST) intervention using ...
4.
bmchealthservres.biomedcentral.com
bmchealthservres.biomedcentral.com/articles/10.1186/s12913-018-3483-1a self-directed coping skills intervention for patients and ...
Current uses and outcomes of hematopoietic stem cell transplantation ... An individualized dyadic problem-solving education intervention ...
Problem-Solving Skills Training for Parents of Children ...
Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Mixed Methods Feasibility Study.
Feasibility and Acceptability of a Couple-Based Physical ...
A couple-based physical activity intervention for hematopoietic cell transplant recipients and their caregiving partners was deemed feasible and acceptable.
7.
nursing.unc.edu
nursing.unc.edu/wp-content/uploads/2025/05/April-2025-Supp-Care-in-Cancer-Transplant-Information.pdfCaregiver experiences managing information prior to ...
This study explores caregivers' experiences and elicits their recommendations for managing transplant-related information during these critical periods. Methods ...
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