Study of Varespladib in Patients Hospitalized With Severe COVID-19
(STAIRS Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have taken investigational medications recently, you may need to wait before enrolling.
What is the purpose of this trial?
This trial tests the safety and effectiveness of an oral medication called varespladib in patients with severe COVID-19. It targets hospitalized patients to help reduce lung damage and inflammation caused by the virus. Varespladib works by blocking an enzyme that contributes to these issues.
Eligibility Criteria
Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive varespladib or placebo in addition to standard of care for 7 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Placebo
- Varespladib
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ophirex, Inc.
Lead Sponsor
Premier Research Group plc
Industry Sponsor
John Ratliff
Premier Research Group plc
Chief Executive Officer since 2024
MBA
Dr. Milena Kanova-Petrova
Premier Research Group plc
Chief Medical Officer since 2024
MD