150 Participants Needed

Motion Reset for Cybersickness in Virtual Reality

Recruiting at 1 trial location
SP
SJ
Overseen BySusan J Persky, Ph.D.
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: National Human Genome Research Institute (NHGRI)

What You Need to Know Before You Apply

What is the purpose of this trial?

Background:People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use.Objective:To see if Motion Reset software can reduce cybersickness in people using VR.Eligibility:Healthy adults aged 18 to 60 years.Design:Participants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers.The study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups:Group 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.Group 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller.Group 3 will have no VR experience.Participants will complete 2 questionnaires about their experiences in the first part of the study.For the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort.After playing the game, participants will complete 12 questionnaires about their experience....

Will I have to stop taking my current medications?

If you are currently using medications or supplements that prevent nausea, like Zofran or Phenergan, you cannot participate in this trial.

Is the Motion Reset treatment for cybersickness in virtual reality generally safe for humans?

The research indicates that cybersickness, which includes symptoms like nausea and discomfort, can occur with virtual reality use, but there is no specific safety data available for the Motion Reset treatment itself. However, it is important to note that symptoms like nausea and discomfort are common with virtual reality exposure.12345

How does the Motion Reset treatment for cybersickness in virtual reality differ from other treatments?

Motion Reset is unique because it uses intentional head motion to align visual and vestibular (balance-related) senses, reducing cybersickness by creating a more natural sense of movement in virtual reality. This approach differs from traditional methods like joystick-based steering or teleportation, which do not engage the user's physical movement in the same way.16789

What data supports the effectiveness of the treatment Motion Reset for cybersickness in virtual reality?

The research on intentional head-motion assisted locomotion shows that aligning visual and physical movements can significantly reduce cybersickness compared to other methods. This suggests that treatments focusing on synchronizing visual and physical cues, like Motion Reset, may be effective in reducing cybersickness.146710

Who Is on the Research Team?

SJ

Susan J Persky, Ph.D.

Principal Investigator

National Human Genome Research Institute (NHGRI)

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 18 to 60 who are interested in participating in a study involving virtual reality (VR). The goal is to see if new software can help prevent the discomfort some people feel after using VR, known as cybersickness.

Inclusion Criteria

Ability to read, speak, and write in English
Provision of signed and dated informed consent form
My hearing is normal or corrected to normal.
See 3 more

Exclusion Criteria

Reporting motion sickness propensity of 0 or 10 on a 0-10 scale where 0 =never experience motion sickness and 10 = experience motion sickness very frequently (self-assessed by participants)
I am currently taking medication to prevent nausea.
I have a history of conditions like seizures or dizziness.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 hour
1 visit (in-person)

Intervention

Participants are assigned to one of three groups to experience VR activities designed to prevent or not prevent cybersickness, or no VR experience.

1 hour
1 visit (in-person)

VR Game Session

All participants play a commercial VR game and are monitored for cybersickness symptoms.

20 minutes
1 visit (in-person)

Follow-up

Participants complete questionnaires about their VR experience and symptoms.

1 hour
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Motion Reset
Trial Overview The trial tests Motion Reset software designed to reduce symptoms of cybersickness against a placebo during VR use. Participants will be divided into groups; one with prevention-focused VR experience, another without it, and a control group with no VR.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Intervention: Motion ResetExperimental Treatment1 Intervention
Group II: No interventionActive Control1 Intervention
Group III: Placebo experiencePlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

National Human Genome Research Institute (NHGRI)

Lead Sponsor

Trials
273
Recruited
299,000+

Citations

Changes in Navigation Controls and Field-of-View Modes Affect Cybersickness Severity and Spatiotemporal Gait Patterns After Exposure to Virtual Environments. [2023]
Does cybersickness affect virtual reality training using the Computer Assisted Rehabilitation Environment (CAREN)? Preliminary results from a case-control study in Parkinson's disease. [2022]
Feasibility and reliability of a virtual reality oculus platform to measure sensory integration for postural control in young adults. [2018]
Intentional Head-Motion Assisted Locomotion for Reducing Cybersickness. [2023]
Estimating the sensorimotor components of cybersickness. [2023]
Cybersickness and postural stability of first time VR users playing VR videogames. [2022]
Accessible virtual reality therapy using portable media devices. [2010]
Characteristic changes in the physiological components of cybersickness. [2022]
Cybersickness: a Multisensory Integration Perspective. [2019]
Cybersickness and Its Severity Arising from Virtual Reality Content: A Comprehensive Study. [2022]
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