24 Participants Needed

Mango for Blood Sugar Control

BK
Overseen ByBryant Keirns, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether replacing table sugar with fresh mango in breakfast meals can help control blood sugar and insulin spikes, which link to diabetes and heart disease. Participants will eat meals with either mango or table sugar, and researchers will measure the impact on blood sugar and vascular health. Ideal participants are those without diabetes or heart disease who can consume mango, wheat, gluten, and milk, and do not use tobacco or certain medications regularly. As an unphased trial, this study offers a unique opportunity to contribute to innovative research on dietary impacts on health.

Will I have to stop taking my current medications?

If you are taking anti-inflammatory drugs more than twice a week, glucose-lowering drugs like metformin, or lipid-lowering drugs like statins, you will need to stop taking them to participate in this trial.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that fresh mango is usually easy to digest and may benefit health. In some studies, participants who ate fresh mango experienced lower blood sugar levels afterward, suggesting mango might help manage blood sugar.

One study found that daily mango consumption could improve the body's insulin use. Insulin is the hormone that controls blood sugar. No major reports of serious side effects have emerged, indicating that fresh mango is safe for most people. However, always consider allergies or dietary needs before trying new foods.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about using fresh mango for blood sugar control because it's a natural and delicious alternative to standard sweeteners like table sugar. Unlike most treatments that rely on synthetic compounds or medications, mango offers a whole food approach with potential health benefits beyond just sweetness. Mango contains unique bioactive compounds and fiber that may help regulate blood sugar levels more effectively and gently than traditional sugar. This could make it a more appealing and health-conscious option for people looking to manage their blood sugar naturally.

What evidence suggests that this trial's treatments could be effective for blood sugar control?

Studies have shown that eating mango can help manage blood sugar levels. One study found that people who ate mangoes daily for 24 weeks had better blood sugar control and improved insulin use. Another study discovered that consuming two cups of fresh mango daily helped overweight adults manage their blood sugar and could benefit heart health. The fiber and natural compounds in mango might contribute to these benefits. In this trial, participants will join different groups to consume either oats or cereal sweetened with fresh mango or table sugar. Overall, replacing table sugar with mango may help maintain steady blood sugar levels after meals.26789

Who Is on the Research Team?

BK

Bryant Keirns, PhD

Principal Investigator

Ball State University

Are You a Good Fit for This Trial?

This trial is for healthy individuals interested in how different breakfasts affect blood sugar and insulin levels. Specific eligibility criteria are not provided, but typically participants should have no major health issues that could interfere with the study.

Inclusion Criteria

Not pregnant (females only)
Does not use tobacco products or any illicit drugs
Does not have a pacemaker
See 11 more

Exclusion Criteria

Body mass index less than 18.5 kg/m2 or greater than 35.0 kg/m2
Pregnant (females only)
Use of tobacco products or any illicit drugs
See 11 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants complete four meal trials in a randomized crossover design, consuming different breakfast meals with either fresh mango or sucrose.

4 weeks
4 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, with measurements of glucose, insulin, and vascular responses.

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Fresh Mango
Trial Overview The study tests the effects of substituting table sugar with fresh mango in breakfast meals on blood sugar, insulin, and vascular responses. Participants will consume low- and high-glycemic meals containing oats or cereal with either mango or table sugar.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Group I: Oat Consumption with Table SugarExperimental Treatment1 Intervention
Group II: Oat Consumption with MangoExperimental Treatment1 Intervention
Group III: Cereal Consumption with Table SugarExperimental Treatment1 Intervention
Group IV: Cereal Consumption with MangoExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ball State University

Lead Sponsor

Trials
10
Recruited
670+

National Mango Board

Collaborator

Trials
7
Recruited
300+

Citations

Daily Mango Intake Improves Glycemic and Body Composition ...Conclusions: The daily consumption of mango for 24 weeks improved the glycemic control, insulin sensitivity, and body composition in adults with prediabetes, ...
Study Details | NCT05571800 | Effect of Mango ...Upon favorable outcomes, and with more definite evidence from human studies, mangoes can potentially be implemented in America's diet to help mitigate the ...
Can a mango a day keep diabetes away - GMU NutritionThe group that consumed the daily mango showed improved blood glucose control, enhanced insulin sensitivity, and reduced body fat. Daily Mango ...
Eat More Mangos, Lower Your Diabetes Risk? New Study ...Eating two cups of fresh mango daily may improve insulin sensitivity and help manage blood sugar in overweight adults, making it a heart-healthy ...
(PDF) Daily Mango Intake Improves Glycemic and Body ...Conclusions: The daily consumption of mango for 24 weeks improved the glycemic control, insulin sensitivity, and body composition in adults with ...
Effects of fresh vs dried mango consumption on satiety and ...There was a significantly lower levels of blood glucose following dried mango and fresh mango consumption at 30 min compared to the control (P < 0.05). At 60- ...
Effects of fresh mango consumption on cardiometabolic ...Mangos may improve certain risk factors associated with overweight and obesity including improved glycemic control and reduced inflammation.
New Study: Eating Mangos Daily Shown to Improve Insulin ...A study recently published in the journal Nutrients finds that eating two cups of mango, just about 100 calories-worth, daily may help lower insulin ...
Can a mango a day keep diabetes awayThe group that consumed the daily mango showed improved blood glucose control, enhanced insulin sensitivity, and reduced body fat.
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