20 Participants Needed

Q-Collar for Healthy Subjects

JA
Overseen ByJ. Andrew Taylor, MS, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Spaulding Rehabilitation Hospital

Trial Summary

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on ongoing active treatment with a cardioactive drug (medication affecting heart function).

What is the purpose of this trial?

The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are:1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance?2. How does the Q-Collar affect brain blood flow during exercise?Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise.Participants will:* Complete two study visits, each 1 to 4 weeks apart.* Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored.* Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.

Research Team

JA

J. Andrew Taylor, MS, PhD

Principal Investigator

Harvard Medical School/Spaulding Rehabilitation Hospital

Eligibility Criteria

This trial is for healthy adults interested in how a device called the Q-Collar might influence brain blood flow during rest and exercise. Participants will be asked to do physical tasks like standing tests, breathing tests, and cycling. They must be available for two study visits spaced 1 to 4 weeks apart.

Inclusion Criteria

I am between 18 and 30 years old and healthy.

Exclusion Criteria

Any current, serious, chronic medical or psychiatric disease that in the Principal Investigator's or co-investigator's judgment may interfere with study participation or data integrity
High cardiac risk according to the American College of Sports Medicine (ACSM)
Pregnancy
See 5 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants complete two study visits, performing standing, breathing, and exercise tests with and without the Q-Collar

1-4 weeks
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks

Treatment Details

Interventions

  • Q30 Q-Collar
Trial Overview The study is testing the effects of the FDA-cleared Q-Collar on regulating brain blood flow when facing quick changes in blood pressure or during exercise. It involves comparing participant's body functions with and without wearing the Q-Collar across different sessions.
Participant Groups
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Cerebrovascular Control with Q-CollarExperimental Treatment1 Intervention
Participants will undergo measurements of cerebral blood flow during changes in body position (sit-to-stand) and resistance breathing tasks while wearing a properly fitted Q-collar to evaluate how the Q-Collar affects cerebrovascular responses to rapid and sinusoidal shifts in blood pressure.
Group II: Cerebrovascular Control without Q-CollarPlacebo Group1 Intervention
Participants will undergo measurements of cerebral blood flow during changes in body position (sit-to-stand) and resistance breathing tasks without wearing a Q-collar.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Spaulding Rehabilitation Hospital

Lead Sponsor

Trials
143
Recruited
11,200+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security