Q-Collar for Healthy Subjects
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on ongoing active treatment with a cardioactive drug (medication affecting heart function).
What is the purpose of this trial?
The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are:1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance?2. How does the Q-Collar affect brain blood flow during exercise?Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise.Participants will:* Complete two study visits, each 1 to 4 weeks apart.* Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored.* Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.
Research Team
J. Andrew Taylor, MS, PhD
Principal Investigator
Harvard Medical School/Spaulding Rehabilitation Hospital
Eligibility Criteria
This trial is for healthy adults interested in how a device called the Q-Collar might influence brain blood flow during rest and exercise. Participants will be asked to do physical tasks like standing tests, breathing tests, and cycling. They must be available for two study visits spaced 1 to 4 weeks apart.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants complete two study visits, performing standing, breathing, and exercise tests with and without the Q-Collar
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Q30 Q-Collar
Find a Clinic Near You
Who Is Running the Clinical Trial?
Spaulding Rehabilitation Hospital
Lead Sponsor