The Effects of Acetaminophen on Fear
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial investigates whether acetaminophen can reduce fear responses in people. It aims to see if the drug can help those with anxiety by making them feel less scared, similar to how it reduces other types of pain.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are taking blood-thinning medications or other products with acetaminophen.
Is acetaminophen (paracetamol) generally safe for humans?
How does the drug acetaminophen differ from other treatments for pain and fever?
Acetaminophen is unique because it is an analgesic (pain reliever) and antipyretic (fever reducer) that does not have anti-inflammatory effects, unlike many other pain medications such as NSAIDs (non-steroidal anti-inflammatory drugs). It is also known for having a low rate of adverse hypersensitivity reactions, making it a safer option for individuals who may have skin reactions to other pain medications.16789
Who Is on the Research Team?
Pat Barclay, Ph.D.
Principal Investigator
University of Guelph
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either 1000 mg acetaminophen or 1000 mg placebo and engage in virtual reality tasks to assess fear responses
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Acetaminophen
- Placebo
Acetaminophen is already approved in United States, European Union, Canada for the following indications:
- Pain relief
- Fever reduction
- Pain relief
- Fever reduction
- Pain relief
- Fever reduction
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Guelph
Lead Sponsor
Natural Sciences and Engineering Research Council, Canada
Collaborator