Acetaminophen Condition for Fear

Phase-Based Progress Estimates

Effectiveness

Safety

University of Guelph, Guelph, Canada

Fear

Acetaminophen - Drug

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Eligibility

18+

All Sexes

What conditions do you have?

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Eligibility

18+

All Sexes

What conditions do you have?

Select

Study Summary

This study investigates the effects of acetaminophen on behavioral, physiological, and self-report fear responses.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Fear

Naltrexone

Acetaminophen

Study Objectives

7 Primary · 3 Secondary · Reporting Duration: 1 hour after taking acetaminophen or placebo

Hour 1

Decision on whether to do the plank walk again with virtual spiders

Distance walked on plank

Heart rate

Proportion of time spent looking down at the plank

Speed towards virtual elevator after turning around on plank

Time before needing a break or quitting the virtual reality plank walk

Time to take first step onto plank

Verbal Self-Report Fear

Walking speed on plank in virtual reality

Written Self-Report Fear

Trial Safety

Safety Progress

1 of 3

Other trials for Fear

Naltrexone

Acetaminophen

Trial Design

2 Treatment Groups

Acetaminophen Condition

1 of 2

Placebo Condition

1 of 2

Experimental Treatment

Non-Treatment Group

266 Total Participants · 2 Treatment Groups

Primary Treatment: Acetaminophen Condition · Has Placebo Group · N/A

Acetaminophen Condition

Drug

Experimental Group · 1 Intervention: Acetaminophen · Intervention Types: Drug

Placebo Condition

Other

PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Other

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Acetaminophen

2017

Completed Phase 4

~2160

Trial Logistics

Trial Timeline

Approximate Timeline

Screening: ~3 weeks

Treatment: Varies

Reporting: 1 hour after taking acetaminophen or placebo

Trial Background

Prof. Patrick Barclay, Professor of Psychology

Principal Investigator

University of Guelph

Closest Location: University of Guelph · Guelph, Canada

2012First Recorded Clinical Trial

1 TrialsResearching Fear

26 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:

You must be at least 18 years old.

You must speak English.\n

About The Reviewer

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References