Acetaminophen Condition for Fear

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Guelph, Guelph, Canada
Fear
Acetaminophen - Drug
Eligibility
18+
All Sexes
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Study Summary

This study investigates the effects of acetaminophen on behavioral, physiological, and self-report fear responses.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Fear

Study Objectives

7 Primary · 3 Secondary · Reporting Duration: 1 hour after taking acetaminophen or placebo

Hour 1
Decision on whether to do the plank walk again with virtual spiders
Distance walked on plank
Heart rate
Proportion of time spent looking down at the plank
Speed towards virtual elevator after turning around on plank
Time before needing a break or quitting the virtual reality plank walk
Time to take first step onto plank
Verbal Self-Report Fear
Walking speed on plank in virtual reality
Written Self-Report Fear

Trial Safety

Safety Progress

1 of 3

Other trials for Fear

Trial Design

2 Treatment Groups

Acetaminophen Condition
1 of 2
Placebo Condition
1 of 2
Experimental Treatment
Non-Treatment Group

266 Total Participants · 2 Treatment Groups

Primary Treatment: Acetaminophen Condition · Has Placebo Group · N/A

Acetaminophen Condition
Drug
Experimental Group · 1 Intervention: Acetaminophen · Intervention Types: Drug
Placebo Condition
Other
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Other
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetaminophen
2017
Completed Phase 4
~2160

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1 hour after taking acetaminophen or placebo

Trial Background

Prof. Patrick Barclay, Professor of Psychology
Principal Investigator
University of Guelph
Closest Location: University of Guelph · Guelph, Canada
2012First Recorded Clinical Trial
1 TrialsResearching Fear
26 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You must be at least 18 years old.
You must speak English.\n

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.