60 Participants Needed

18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer

SH
Overseen BySteven H Lin, MD, PHD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

This study is being done to learn how 18F-FSPG PET/CT scan results may be related to the response to chemotherapy and radiation in patients with esophageal cancer.

Research Team

SH

Steven H Lin, MD, PHD

Principal Investigator

M.D. Anderson Cancer Center

Eligibility Criteria

Inclusion Criteria

I can sign and understand the consent form.
I am a woman able to have children and have a recent negative pregnancy test.
My esophageal cancer has not spread far from its original site.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 18F-FSPG IV and undergo PET/CT scans during standard of care radiation therapy

3 weeks
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

48 weeks

Treatment Details

Participant Groups
1Treatment groups
Experimental Treatment
Group I: ObservationalExperimental Treatment1 Intervention
Patients receive 18F-FSPG IV and undergo a PET/CT scan. During week 3 of standard of care radiation therapy, patients receive 18F-FSPG and undergo a second PET/CT scan on study.

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+
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