← Back to Search

Extended Antibiotics for Penile Prosthesis Infection (CUPID Trial)

Phase < 1
Waitlist Available
Led By Sarah Faris, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

CUPID Trial Summary

This trial will test whether 6 extra days of antibiotics can lower the risk of infection for men getting a penile prosthesis.

Who is the study for?
This trial is for males aged 35-90 with erectile dysfunction who are getting a specific penile prosthesis (AMS 700) and haven't used antibiotics in the last week. It's not for those with prior prostheses, urinary tract foreign bodies, urethral strictures, tuberculosis-related cystitis, recent chemotherapy, bladder surgery history or systemic neuromuscular diseases.Check my eligibility
What is being tested?
The study tests if taking oral antibiotics (Doxycycline, Augmentin, Bactrim or Ciprofloxacin) for an extra six days after implanting a penile prosthesis can reduce infection risk. Participants will receive one of these antibiotics to see which is most effective.See study design
What are the potential side effects?
Possible side effects from the antibiotics may include stomach upset like nausea and diarrhea; allergic reactions such as rashes; yeast infections; and rarely more serious issues like tendon problems or nerve damage.

CUPID Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Additional 6 days of oral antibiotics after Penile prothesis placement does not decrease the risk of device infection leading to surgical intervention
Secondary outcome measures
Additional 6 days of oral antibiotics after Penile prosthesis placement does not decrease the risk of superficial tissue infections after penile prothesis implantation.

CUPID Trial Design

2Treatment groups
Active Control
Group I: No post-operative oral antibioticsActive Control1 Intervention
Patients will only receive 24hr of IV peri-operative antibiotics
Group II: 6 days of oral antibioticsActive Control4 Interventions
Patients will receive 24hr of IV peri-operative antibiotics and then 6 days of oral antibiotics

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor
995 Previous Clinical Trials
815,868 Total Patients Enrolled
1 Trials studying Erectile Dysfunction
1 Patients Enrolled for Erectile Dysfunction
Loyola UniversityOTHER
156 Previous Clinical Trials
30,622 Total Patients Enrolled
Sarah Faris, MDPrincipal InvestigatorUniversity of Chicago Department of Surgery

Media Library

6 days of oral antibiotics Clinical Trial Eligibility Overview. Trial Name: NCT05100654 — Phase < 1
Erectile Dysfunction Research Study Groups: No post-operative oral antibiotics, 6 days of oral antibiotics
Erectile Dysfunction Clinical Trial 2023: 6 days of oral antibiotics Highlights & Side Effects. Trial Name: NCT05100654 — Phase < 1
6 days of oral antibiotics 2023 Treatment Timeline for Medical Study. Trial Name: NCT05100654 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to be included in this research program?

"This clinical trial seeks 800 participants, aged 35 to 90 years old, who are currently struggling with erectile dysfunction. To be eligible for enrollment in the study individuals must meet several criteria including: Males age-appropriate and clinically indicated for InhibiZonetm coated AMS 700 devices IPP placement procedure per local guidelines who have chosen penile prosthesis as a treatment option; males of all races and ethnicities between 35 -90 years of age dealing with ED diagnosis."

Answered by AI

What is the current number of participants in this research trial?

"Affirmative. The information posted on clinicaltrials.gov affirms that this experiment is still looking for patients to enrol in the study; it was initially presented on April 22nd 2022 and edited lastly on April 27th 2022, with a target of 800 participants from one medical centre."

Answered by AI

What conditions typically warrant a six-day course of oral antibiotics?

"In many cases, 6 days of oral antibiotics are prescribed for cysto-urethritis. The same treatment is also accepted in the medical community to combat q fever, severe acne and otitis externa."

Answered by AI

Are recruitment efforts for this trial still ongoing?

"As presented on clinicaltrials.gov, the medical trial is in its recruitment phase and was first posted on April 22nd 2022 with an update occurring 5 days later."

Answered by AI

Is eligibility for the experiment limited to individuals who have reached majority?

"As outlined by the criteria for this clinical trial, participants need to be aged at least 35 and no more than 90."

Answered by AI
~225 spots leftby Dec 2024