Intracranial Monitoring Tasks for Language Disorders
Trial Summary
What is the purpose of this trial?
Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light on the construction and understanding of speech.
Do I need to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Behavioral tasks during intracranial monitoring for language disorders?
Research shows that using advanced language mapping techniques, like computerized platforms during brain surgery, can improve the detection and understanding of language deficits. This suggests that similar behavioral tasks during intracranial monitoring could be effective in identifying and managing language disorders.12345
Is intracranial monitoring for language disorders safe for humans?
The research does not provide specific safety data for intracranial monitoring tasks for language disorders, but a related study on transcranial direct current stimulation (tDCS) for language treatment in stroke survivors reported no serious adverse events, suggesting that similar non-invasive brain monitoring techniques may be safe.12678
How does this treatment for language disorders differ from other treatments?
This treatment uses a novel computerized platform for language mapping during brain surgery, which is unique because it allows for more precise and flexible assessment of language function compared to traditional methods. It integrates with preoperative imaging and intraoperative testing to better identify and characterize language deficits, making it particularly useful during awake brain surgeries.134910
Eligibility Criteria
This trial is for adults aged 18-85 with language disorders or epilepsy who are already scheduled for intracranial monitoring of the left cerebral hemisphere. Participants must be able to follow test instructions and give informed consent.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intracranial Monitoring
Neural responses to language stimuli are collected from epileptic patients undergoing intracranial monitoring
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Behavioral tasks during intracranial monitoring
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor
Massachusetts Institute of Technology
Collaborator