← Back to Search

Intracranial Monitoring Tasks for Language Disorders

N/A

Recruiting

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Between ages 18 - 85

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up throughout intracranial monitoring period, up to approximately 10 days

Awards & highlights

Study Summary

This trial will help researchers understand how the brain processes speech, which could lead to new treatments for speech disorders.

Who is the study for?

This trial is for adults aged 18-85 with language disorders or epilepsy who are already scheduled for intracranial monitoring of the left cerebral hemisphere. Participants must be able to follow test instructions and give informed consent.Check my eligibility

What is being tested?

The study investigates how the human brain processes language by having participants perform behavioral tasks during intracranial monitoring, aiming to combine neural data with computational models of cognition.See study design

What are the potential side effects?

Since this trial involves non-invasive behavioral tasks during a procedure that patients are already undergoing, there are no additional side effects directly associated with the study itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 85 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ throughout intracranial monitoring period, up to approximately 10 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~throughout intracranial monitoring period, up to approximately 10 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout intracranial monitoring period, up to approximately 10 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Brain scores for diverse artificial neural network (ANN) language models

Cortical maps of linguistic responses

Neural time-courses during naturalistic language comprehension

Trial Design

1Treatment groups

Experimental Treatment

Group I: Epileptic participants undergoing intracranial monitoringExperimental Treatment1 Intervention

Patients with pharmaco-resistant epilepsy undergoing intracranial monitoring involving the left cerebral hemisphere.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,933 Previous Clinical Trials

13,198,461 Total Patients Enrolled

Massachusetts Institute of TechnologyOTHER

97 Previous Clinical Trials

12,729,947 Total Patients Enrolled

Media Library

Epileptic participants undergoing intracranial monitoring Clinical Trial Eligibility Overview. Trial Name: NCT05222594 — N/A

Language Disorder Research Study Groups: Epileptic participants undergoing intracranial monitoring

Language Disorder Clinical Trial 2023: Epileptic participants undergoing intracranial monitoring Highlights & Side Effects. Trial Name: NCT05222594 — N/A

Epileptic participants undergoing intracranial monitoring 2023 Treatment Timeline for Medical Study. Trial Name: NCT05222594 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the total number of participants being included in this clinical research?

"Affirmative. The information on clinicaltrials.gov attests to this medical trial's active recruitment of participants, which commenced on April 2nd 2021 and was recently updated February 10th 2022. This research project needs 40 people to be recruited at a single location."

Answered by AI

Does your research accept participants aged 55 and over?

"To be eligible for this trial, applicants must fall within the age range of 18 and 85. Additionally, 106 studies are recruiting participants younger than 18 years old whereas 160 trials seek those older than 65."

Answered by AI

Who qualifies to become an enrollee in this experiment?

"In order to be considered, applicants must possess the capacity for language and meet age criteria (18-85). This study is looking to accept a total of 40 individuals."

Answered by AI

Is enrollment currently open for the trial?

"Indeed, the information found on clinicaltrials.gov reveals that this research is currently accepting enrollees. Initially posted on April 2nd 2021 and recently amended at February 10th 2022, 40 patients are sought from a single location."

Answered by AI

Recent research and studies

NeuroscienceJournal

An Attempt to Conceptually Replicate the Dissociation Between Syntax and Semantics During Sentence Comprehension

Siegelman, Matthew, Idan A. Blank, Zachary Mineroff, and Evelina Fedorenko. 2019. “An Attempt to Conceptually Replicate the Dissociation Between Syntax and Semantics During Sentence Comprehension”. Neuroscience. Elsevier BV. doi:10.1016/j.neuroscience.2019.06.003.

NeuropsychologiaJournal

Lexical and Syntactic Representations in the Brain: An Fmri Investigation with Multi-voxel Pattern Analyses

Fedorenko, Evelina, Alfonso Nieto-Castañon, and Nancy Kanwisher. 2012. “Lexical and Syntactic Representations in the Brain: An Fmri Investigation with Multi-voxel Pattern Analyses”. Neuropsychologia. Elsevier BV. doi:10.1016/j.neuropsychologia.2011.09.014.

Nature CommunicationsJournal

Toward a Universal Decoder of Linguistic Meaning from Brain Activation

Pereira, Francisco, Bin Lou, Brianna Pritchett, Samuel Ritter, Samuel J. Gershman, Nancy Kanwisher, Matthew Botvinick, and Evelina Fedorenko. 2018. “Toward a Universal Decoder of Linguistic Meaning from Brain Activation”. Nature Communications. Springer Science and Business Media LLC. doi:10.1038/s41467-018-03068-4.

Trends in Cognitive SciencesJournal