Genetic Testing Interventions for Cancer Risk
(MiGHT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if two new methods can help people receive appropriate genetic testing for cancer risk. The study compares a virtual genetics tool (Virtual Genetics Navigator) and motivational phone calls (Motivational Interviewing) with usual care to identify which method better aids individuals in understanding and pursuing genetic testing. It seeks participants who have had certain cancers, such as breast or prostate cancer diagnosed before age 50, or those with specific family histories of cancer. Participants should not have undergone genetic testing for cancer. As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance access to and understanding of genetic testing.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It seems focused on genetic testing interventions, so it's unlikely that your medications would be affected, but you should confirm with the trial organizers.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that motivational interviewing (MI), a method used in healthcare, is well-received by patients. Studies have found that MI helps people make informed choices about genetic testing without causing harm or discomfort. No reports of negative side effects have emerged from using MI in this setting.
Early results suggest that the virtual genetics navigator is also safe to use. This tool aids patients in understanding genetic testing by providing information and support, with no reported negative effects. Its goal is to facilitate learning and decision-making, not to provide medical treatment.
Both methods in the study aim to support decision-making without health risks.12345Why are researchers excited about this trial?
Researchers are excited about these interventions for genetic testing in cancer risk management because they employ innovative approaches aimed at increasing patient engagement. Motivational interviewing (MI) stands out as it involves personalized phone calls from genetics health coaches who use motivational techniques to encourage individuals to pursue genetic testing. This method is more interactive and supportive compared to standard informational approaches. The Virtual Genetics Navigator offers a novel digital tool that empowers patients by providing easy-to-understand information online, helping them make informed decisions about genetic testing for hereditary cancer syndromes. These methods could significantly enhance patient understanding and motivation compared to traditional care, which typically involves self-directed information gathering without personalized guidance.
What evidence suggests that this trial's interventions could be effective for increasing genetic testing?
This trial will compare different interventions to encourage genetic testing for cancer risk. Participants in one arm will receive motivational interviewing (MI), where trained genetics health coaches provide information and encouragement through phone calls. Studies have shown that MI can increase the number of people undergoing cancer screening tests, such as those for breast and cervical cancer. Research indicates that MI effectively helps more people follow through with recommended screenings.
Another arm of the trial will provide participants with access to a virtual genetics navigator, an online tool designed to educate and guide users about genetic testing. Research suggests that such digital platforms can significantly improve testing rates by helping people understand their cancer risk and the importance of genetic testing. Initial findings show that these tools can more than double the number of people completing genetic testing.13467Who Is on the Research Team?
Elena Stoffel, MD
Principal Investigator
University of Michigan Rogel Cancer Center
Are You a Good Fit for This Trial?
This trial is for English-speaking adults in Michigan with a history of certain cancers (breast, ovarian, endometrial, colorectal, prostate or pancreatic) who haven't had genetic testing yet. They must have internet access and meet specific clinical criteria for genetic evaluation based on their cancer type and family history.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants are randomized to one of three interventions: Virtual genetics navigator, motivational interviewing calls, or usual care.
Follow-up
Participants are monitored for completion of genetic testing and surveyed on barriers and motivators at 6 and 12 months.
What Are the Treatments Tested in This Trial?
Interventions
- Motivational interviewing (MI)
- Virtual genetics navigator
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan Rogel Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator