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Genetic Testing Interventions for Cancer Risk (MiGHT Trial)

N/A
Recruiting
Led By Elena Stoffel, MD, MPH
Research Sponsored by University of Michigan Rogel Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months after enrollment/randomization
Awards & highlights

MiGHT Trial Summary

This trial is testing whether two experimental interventions (a website and motivational phone calls) increase the likelihood of patients getting genetic testing recommended by medical guidelines, compared to receiving usual care.

Who is the study for?
This trial is for English-speaking adults in Michigan with a history of certain cancers (breast, ovarian, endometrial, colorectal, prostate or pancreatic) who haven't had genetic testing yet. They must have internet access and meet specific clinical criteria for genetic evaluation based on their cancer type and family history.Check my eligibility
What is being tested?
The study compares three methods to see if they increase the likelihood of getting recommended genetic testing: a virtual genetics navigator website with tailored content; motivational interviewing calls by trained coaches; or usual care without these interventions.See study design
What are the potential side effects?
Since this trial involves non-invasive interventions like educational resources and counseling calls rather than medications or medical procedures, there are no typical side effects associated with participation.

MiGHT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months after enrollment/randomization
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months after enrollment/randomization for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percentage of participants who complete clinical genetic testing at six months after randomization
Secondary outcome measures
Barriers to genetic testing, for participants who completed genetic testing
Barriers to genetic testing, for participants who did not yet complete genetic testing
Motivators of genetic testing, for participants who completed genetic testing
+1 more

MiGHT Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Arm 3 - Motivational interviewing (MI)Experimental Treatment1 Intervention
Participants receive up to 2 phone calls from trained genetics health coaches who provide information about genetic testing and use motivational interviewing to encourage participants to seek out clinical genetic testing.
Group II: Arm 2 - Virtual genetics navigatorExperimental Treatment1 Intervention
Participants receive access to an online genetics tool, the virtual genetics navigator, to help learn why and how to seek out genetic testing for hereditary cancer syndromes.
Group III: Arm 1 - Usual care (UC)Active Control1 Intervention
Participants are provided with a link to the Michigan Department of Health and Human Services (MDHHS) informational website and are instructed to follow up with their oncology provider about genetic testing.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Motivational interviewing (MI)
2007
N/A
~400

Find a Location

Who is running the clinical trial?

University of Michigan Rogel Cancer CenterLead Sponsor
292 Previous Clinical Trials
23,306 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,627 Previous Clinical Trials
40,927,076 Total Patients Enrolled
Elena Stoffel, MD, MPHPrincipal InvestigatorUniversity of Michigan Rogel Cancer Center

Media Library

Motivational interviewing (MI) Clinical Trial Eligibility Overview. Trial Name: NCT05162846 — N/A
History of Cancer Research Study Groups: Arm 1 - Usual care (UC), Arm 2 - Virtual genetics navigator, Arm 3 - Motivational interviewing (MI)
History of Cancer Clinical Trial 2023: Motivational interviewing (MI) Highlights & Side Effects. Trial Name: NCT05162846 — N/A
Motivational interviewing (MI) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05162846 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current scale of enrolment for this research trial?

"Affirmative. The clinicaltrials.gov page contains information that this study has been enrolling patients since April 21st 2022, with the latest update happening on May 31st 2022. This trial is currently recruiting 759 participants from one medical centre."

Answered by AI

Are participants being recruited for this experiment currently?

"Current information on clinicaltrials.gov affirms that this scientific trial is currently looking for participants, which it initially called for in April of 2022 and most recently updated at the end of May."

Answered by AI
~343 spots leftby Nov 2025