Nicotine Reduction for Vaping Addiction
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to see if reducing nicotine in e-cigarettes can make them less addictive for young users. Researchers will test different levels of nicotine reduction to find out if it helps decrease usage and dependence. The study focuses on young people because they are increasingly using e-cigarettes and are at high risk of addiction.
Will I have to stop taking my current medications?
Yes, if you regularly use prescription medications (other than vitamins or birth control), you will not be eligible to participate in this trial.
Is reducing nicotine in e-cigarette liquids safe for humans?
How does the nicotine reduction treatment for vaping addiction differ from other treatments?
What data supports the effectiveness of the treatment for vaping addiction?
Research suggests that reducing nicotine concentration in e-cigarette liquids may lead users to seek alternative products or adjust their usage, which could potentially help in reducing dependence. Additionally, the combination of nicotine content and flavors plays a role in how people respond to e-cigarettes, indicating that managing these factors could influence vaping habits.138910
Who Is on the Research Team?
Wasim Maziak, PhD, MD
Principal Investigator
Florida International University
Are You a Good Fit for This Trial?
This trial is for healthy adults aged 21-35 who use electronic cigarettes, can attend lab sessions, and have not used e-cigarettes for 12 hours before each visit. Pregnant or breastfeeding women, THC users, those with COVID-19 symptoms or exposure, regular tobacco/nicotine product users in the past year, people with chronic diseases or psychiatric conditions are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment Part 1
Participants use NJOY 5% and 3% nicotine electronic cigarette pods to test the effects of partial nicotine reduction
Treatment Part 2
Participants use NIDA Standardized Research Electronic Cigarette (SREC) 5% and 0% nicotine pods to test the effects of total nicotine reduction
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- 0% nicotine
- 3% nicotine
- 5% nicotine
0% nicotine is already approved in United States, European Union for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida International University
Lead Sponsor