Lentils + Chickpeas for Imbalance of Microbes
Trial Summary
What is the purpose of this trial?
The primary goal of this research is to evaluate the effect of daily whole-cooked chickpea and lentil consumption for 8-weeks on gut health, including microbiome-metabolome arrays and gut epithelial/barrier function, in healthy young adults. Secondary Objectives include: * To examine the effect of daily whole-cooked chickpea and lentil consumption for 8-weeks on the measures of metabolic health and inflammation in healthy young adults. * To determine the feasibility of healthy young adults to successfully incorporate and sustain the recommended daily intake of pulses into their diets for eight consecutive weeks Research Interventions: Participants will be asked to consume a normal diet supplemented daily with either A) whole-cooked canned lentils, or B) whole-cooked canned chickpeas. The control condition will be instructed to consume a normal diet while restricting all pulse intake throughout the study.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have been taking antibiotics or pre/pro/postbiotics in the last 3 months, you would not be eligible to participate.
What data supports the effectiveness of the treatment Whole-cooked Chickpeas, Whole-cooked Lentils for Imbalance of Microbes?
Research shows that diets supplemented with chickpeas can positively change the gut bacteria in healthy adults, potentially promoting intestinal health. Additionally, chickpea supplementation in mice reduced inflammation and improved gut health, suggesting that chickpeas may help balance gut microbes.12345
Is it safe to consume lentils and chickpeas for gut health?
How does the treatment of whole-cooked chickpeas and lentils for microbial imbalance differ from other treatments?
This treatment is unique because it uses whole-cooked chickpeas and lentils, which are natural foods rich in dietary fiber, to help balance gut microbes. Unlike other treatments that might involve medications or supplements, this approach leverages the natural properties of these legumes to promote a healthier gut microbiome, potentially improving intestinal health without the need for synthetic interventions.1891011
Research Team
Ravinder Nagpal, Ph.D.
Principal Investigator
Florida State University
Eligibility Criteria
This trial is for healthy young adults interested in the effects of lentils and chickpeas on gut health. Participants should be willing to add these foods to their daily diet or restrict pulse intake if assigned to the control group. Specific eligibility criteria are not provided, but typically participants must meet certain health standards.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume a normal diet supplemented daily with either whole-cooked canned lentils or chickpeas for 8 weeks
Follow-up
Participants are monitored for changes in gut microbiome, metabolic health, and other health markers after treatment
Treatment Details
Interventions
- Whole-cooked Chickpeas
- Whole-cooked Lentils
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida State University
Lead Sponsor
United States Department of Agriculture (USDA)
Collaborator
USDA ARS
Collaborator