Treatment for Intractable Epilepsy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Intractable EpilepsyRNS/DBS activation - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy

Eligible Conditions
  • Intractable Epilepsy

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 1 Secondary · Reporting Duration: Baseline, post intervention (about 2 hours after baseline )

Hour 2
Change in amplitude of evoked potentials metrics as assessed by the scalp EEG
Electroencephalography
Hour 2
Change in reaction time to visual stimuli measured as vigilance score assessed by the Psychomotor Vigilance test (PVT)

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Treatment
1 of 1

Experimental Treatment

25 Total Participants · 1 Treatment Group

Primary Treatment: Treatment · No Placebo Group · N/A

Treatment
Device
Experimental Group · 1 Intervention: RNS/DBS activation · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, post intervention (about 2 hours after baseline )

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor
809 Previous Clinical Trials
256,160 Total Patients Enrolled
Sandipan Pati, MDPrincipal InvestigatorThe University of Texas Health Science Center, Houston

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are undergoing neuromodulation therapy with clinically implanted neuromodulation devices (DBS, RNS).