Neuronal Mechanisms for Epilepsy

MC
Overseen ByMia Coordinator
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Cedars-Sinai Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to examine how memories of past experiences are used to guide behavior in novel situations through the cognitive process of abstraction. This project examines how abstract representations are learned, whether and how they support generalization to novel situations, and whether and how they support analogical reasoning.

Who Is on the Research Team?

AM

Adam Mamelak, MD

Principal Investigator

Cedars-Sinai Medical Center

UR

Ueli Rutishauser, PhD

Principal Investigator

Cedars-Sinai Medical Center

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 18 years old or older.
Full Scale Intelligence Quotient > 70
Intractable epilepsy patients undergoing invasive monitoring
See 1 more

Exclusion Criteria

Determination by clinicians and investigators that a patient is unable to complete the behavioral tasks required for the protocol due to either cognitive limits, psychological limits, or pain.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo behavioral testing and neuronal recordings while conducting cognitive tests during their hospital stay

3 years

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Behavioral TestingExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Cedars-Sinai Medical Center

Lead Sponsor

Trials
523
Recruited
165,000+

University of California, Los Angeles

Collaborator

Trials
1,594
Recruited
10,430,000+

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborator

Trials
377
Recruited
190,000+

University of California, Davis

Collaborator

Trials
958
Recruited
4,816,000+

Barrow Neurological Institute

Collaborator

Trials
27
Recruited
7,100+

Columbia University

Collaborator

Trials
1,529
Recruited
2,832,000+