Community Eye Screening for Vision Loss Prevention
(VIEW II Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to find the best way to prevent blindness by comparing two different eye screening programs. One program uses advanced technology, such as OCT (a special eye scan), to screen for conditions like glaucoma and diabetic retinopathy while connecting patients to care. The other program focuses on a basic vision test. Residents aged 50 and older in urban or nearby areas of Bharatpur or Lumbini, accessible by regular vehicles, can participate.
As an unphased trial, this study offers participants the chance to contribute to important research that could enhance eye care for many.
Do I need to stop my current medications for this eye screening trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to consult with the trial coordinators or your doctor for guidance.
What prior data suggests that these screening methods are safe for vision loss prevention?
Research shows that the screening methods used in this trial are generally safe for people.
For checking eye pressure, studies have found that this method is well-tolerated, with various safe devices available for patients. This test is a standard part of eye exams and is considered reliable.
Optical coherence tomography (OCT) serves as another important tool in the trial. This non-invasive imaging technique is widely used to diagnose and monitor eye diseases. Studies confirm that OCT is safe and suitable for most people.
Visual acuity tests, such as reading a Snellen chart, are also safe and commonly used to assess vision. These simple tests involve reading letters from a distance and are part of routine eye exams.
Overall, these screening methods are safe and widely used in eye care. They are designed to detect eye problems without causing harm to patients.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to improve early detection and prevention of vision loss by using a combination of advanced screening techniques. Unlike traditional eye exams that might focus solely on visual acuity, this approach includes measuring intraocular pressure and using optical coherence tomography (OCT) to get detailed images of the retina. These methods allow for a more comprehensive assessment of eye health, potentially catching issues that other standard methods might miss. This could lead to earlier interventions and better outcomes for individuals at risk of vision loss.
What evidence suggests that this trial's screening methods could be effective for preventing vision loss?
Research has shown that optical coherence tomography (OCT), a method used in this trial, is a powerful tool for diagnosing eye diseases. OCT provides clear and detailed images, effectively identifying conditions like glaucoma, diabetic retinopathy, and age-related macular degeneration. Studies have found that OCT accurately detects diseases and reduces the chances of false alarms. Checking eye pressure, another method in this trial, can also help detect glaucoma early, potentially preventing severe vision loss. While vision tests, also part of this trial, are effective for noticing changes in sight, they might not catch all causes of vision loss. Together, these methods can improve early detection and treatment, helping to prevent or slow down vision loss.678910
Who Is on the Research Team?
Jeremy Keenan
Principal Investigator
University of California, San Francisco
Are You a Good Fit for This Trial?
This trial is for communities in the catchment areas of Bharatpur Eye Hospital or Lumbini Eye Institute that are reachable by non-4WD vehicles, including urban and peri-urban locations. It aims to include a broad demographic to assess eye health strategies.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Initial door-to-door census to assess baseline visual acuity in both study arms
Intensive Screening
Screening with OCT, fundus photography, and intraocular pressure testing for glaucoma, DR, and AMD, followed by enhanced linkage-to-care
Follow-up
Repeat visual acuity assessment 9 years later to compare visual acuity between the two arms
What Are the Treatments Tested in This Trial?
Interventions
- Active linkage to care
- Intraocular pressure
- Optical coherence tomography (OCT)
- Visual acuity (presenting and pinhole)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor
Lumbini Eye Institute and Hospital
Collaborator
Seva Foundation
Collaborator
Bharatpur Eye Hospital
Collaborator