Injection Ports vs Single-Use Needles for Gestational Diabetes

JM
Overseen ByJessica Montgomery, MD
Age: 18 - 65
Sex: Female
Trial Phase: Academic
Sponsor: University of Texas at Austin
Must be taking: Insulin
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines whether using an injection port for insulin during pregnancy improves diabetes management compared to regular needles. Injection ports deliver insulin through the same spot, reducing the need for multiple daily injections and potentially making insulin administration easier and less painful. The trial aims to determine if this method enhances satisfaction with treatment and adherence to insulin plans. It targets pregnant individuals with type 2 or gestational diabetes who require multiple daily insulin doses. As an unphased trial, this study provides a unique opportunity to explore innovative methods for improving diabetes management during pregnancy.

Do I need to stop my current medications for this trial?

The trial information does not specify if you need to stop your current medications. It focuses on using an injection port for insulin delivery, so you may continue your insulin regimen as prescribed.

What prior data suggests that this injection port is safe for insulin use during pregnancy?

Studies have shown that injection ports are generally well-tolerated by patients, including pregnant individuals using them for medications other than insulin. These ports allow insulin administration without multiple daily needle pokes, reducing discomfort and simplifying adherence to insulin treatment plans.

No specific studies have yet examined the use of injection ports for insulin during pregnancy. However, since these devices are already used safely for other medications, experts believe they are likely safe for insulin as well. The injection port functions the same way for insulin as it does for other medicines, which supports its safety.

For those considering joining a trial using injection ports, it is reassuring to know that these devices have proven helpful and safe for many in similar situations.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores the use of injection ports for managing gestational diabetes, offering a potential break from the routine of daily needle sticks. Unlike standard single-use insulin needles that require a fresh needle for each dose, injection ports allow multiple insulin doses through a single device, reducing needle pricks to just once every few days. This not only minimizes discomfort but could also enhance the convenience of managing insulin therapy during pregnancy. By comparing these two methods, researchers hope to find out if injection ports can improve the quality of life for expecting mothers who need insulin therapy.

What evidence suggests that injection ports are effective for gestational diabetes?

This trial will compare injection ports with single-use insulin needles for managing gestational diabetes. Research has shown that insulin pumps can help pregnant women with diabetes manage blood sugar levels more effectively. Specifically, women using these pumps demonstrated improved HbA1c levels, indicating better long-term blood sugar control, and experienced fewer serious episodes of low blood sugar. Although an injection port differs from an insulin pump, it also simplifies insulin administration. This could make insulin management during pregnancy easier and less painful, potentially improving health outcomes for both mother and baby.16789

Who Is on the Research Team?

LH

Lorie Harper

Principal Investigator

University of Texas at Austin, Dell Medical School

Are You a Good Fit for This Trial?

This trial is for pregnant individuals with diabetes (gestational, type 1, or insulin resistance) who need to manage their blood sugar levels with insulin. The study aims to include those who are looking for potentially more comfortable and convenient ways of administering insulin.

Inclusion Criteria

I have type 2 or gestational diabetes and need multiple daily insulin shots.

Exclusion Criteria

My primary language is neither English nor Spanish.
Patients with T1DM
Patients using an insulin pump

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants administer insulin using either injection ports or single-use needles for two weeks

2 weeks
1 visit (in-person) for device training and setup

Follow-up

Participants are monitored for compliance, satisfaction, glucose control, hypoglycemia episodes, adverse reactions, and device malfunctions

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Injection Port
  • Single-Use Insulin Needles
Trial Overview The study is testing whether using an injection port—a device that allows repeated insulin injections through the same spot on the skin—improves adherence to treatment and patient satisfaction compared to single-use needles during pregnancy.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Injection portExperimental Treatment1 Intervention
Group II: Single-use insulin needlesActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Texas at Austin

Lead Sponsor

Trials
387
Recruited
86,100+

Citations

Injection Ports vs Single-Use Needles for Insulin in ...This study aims to assess patient satisfaction with the use of injection ports for insulin administration among pregnant patients with diabetes.
Management of Diabetes in Pregnancy: A Review ...It showed that women receiving insulin pumps had much better HbA1c levels, fewer severe hypoglycemic events by 35%, and fewer rates of neonatal ...
Approach to the Patient Using Diabetes Technology in ...Recent randomized controlled trials have demonstrated improved glycemic outcomes with use of HCL insulin pumps in pregnancy with T1D, though the results vary ...
Time in Range in Pregnancy: Is There a Role?Trials of CGM Use During Pregnancy in Women With Type 2 Diabetes or GDM. Outcomes data for the use of CGM in type 2 diabetes and GDM are far ...
have pregnancy outcomes in women with type 1 diabetes ...The aim of this study was to compare metabolic control and neonatal outcomes in pregnant women with T1DM among different basal insulins (NPH vs. analogue)
Diabetes Mellitus in Pregnancy: Implications for Obstetric ...For individuals with T2DM, emerging data suggest that CGM devices may be associated with decreased neonatal morbidity, fewer preterm births, and ...
Top Gestational Diabetes Clinical Trials | PowerThis study wants to find out if using an injection port to give insulin during pregnancy helps people take their insulin more regularly and feel better about ...
University of Groningen Efficacy and safety of metformin ...Evidence indicates possible altered fetal programming and predisposition to childhood obesity and metabolic syndrome during adulthood after use ...
Diabetes in pregnancy: a new decade of challenges aheadWomen with pregestational type 1 and type 2 diabetes mellitus continue to have poorer pregnancy outcomes than the background population, including a three- to ...
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