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Brain Stimulation for Dyslexia

Research Sponsored by Georgia State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Normal or corrected to normal vision
Be younger than 65 years old
Must not have
Hearing deficits (>25 decibels at 500+ Hz), visual deficits (>20/40), serious emotional problems (e.g., severe, uncontrolled depression) and certain neurological conditions (e.g., uncontrolled seizure disorders)
Individuals taking certain medications that lower seizure threshold
Screening 3 weeks
Treatment Varies
Follow Up immediately following ctbs
Awards & highlights


This trial aims to use a technique called transcranial magnetic stimulation (TMS) to study how older youth learn spoken words. The study will focus on how inhibiting a specific part of the brain

Who is the study for?
This trial is for older youth with dyslexia. Participants should be able to undergo brain stimulation and are interested in how it might affect learning new spoken words. Specific eligibility details aren't provided, so generally healthy individuals who meet the age requirement for 'older youth' may apply.Check my eligibility
What is being tested?
The study tests if a type of brain stimulation called cTBS can influence learning, processing, and remembering made-up words that sound similar. Some participants will receive real cTBS while others get a sham (fake) treatment to compare results.See study design
What are the potential side effects?
While specific side effects are not listed, TMS can sometimes cause discomfort at the stimulation site, headache, lightheadedness or seizures in very rare cases.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
My vision is normal or corrected to normal with glasses or contacts.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
I do not have severe hearing, vision, emotional, or uncontrolled neurological conditions.
I am taking medication that could increase my risk of seizures.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Novel Word Learning Task
Pseudoword Discrimination Task
Secondary outcome measures
MRI Scan

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active cTBSExperimental Treatment1 Intervention
Active cTBS will be administered to the left supramarginal gyrus
Group II: Sham stimulationPlacebo Group1 Intervention
Sham stimulation will be administered to the left supramarginal gyrus

Find a Location

Who is running the clinical trial?

Georgia State UniversityLead Sponsor
60 Previous Clinical Trials
29,103 Total Patients Enrolled
2 Trials studying Dyslexia
478 Patients Enrolled for Dyslexia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH
1,988 Previous Clinical Trials
2,683,483 Total Patients Enrolled
10 Trials studying Dyslexia
6,054 Patients Enrolled for Dyslexia
~13 spots leftby Oct 2024