Master Platform for Mood Disorders
(ENABLE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores new ways to match treatments to individuals with mood disorders such as depression and bipolar disorder. The researchers aim to collect data to identify "biomarkers," which are bodily clues that can help doctors find the best treatment more quickly. By creating a large pool of participants, the trial seeks to accelerate the discovery of effective treatments through biomarker-based studies. Individuals diagnosed with bipolar or depressive disorders who speak English well are suitable candidates for this trial. As an unphased study, this trial offers participants the chance to contribute to groundbreaking research that could lead to more personalized and effective treatments for mood disorders.
Why are researchers excited about this trial?
The "Innovative Master Platform for Clinical Trials in Mood Disorders" is exciting because it offers a new way to study treatments for conditions like depression and bipolar disorder. Instead of testing one treatment at a time, this platform allows researchers to test multiple treatments simultaneously, speeding up the process of finding effective therapies. This approach can lead to quicker identification of which treatments work best for different patients, potentially offering more personalized and effective options compared to traditional methods. Researchers are hopeful that this could revolutionize how mood disorders are treated, providing faster relief for patients who need it.
Who Is on the Research Team?
Benicio N Frey
Principal Investigator
St. Joseph's Healthcare Hamilton
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Tier 1 Assessment
Participants complete clinical assessments, including clinician-administered and self-report measures
Tier 2 Assessment
Participants provide blood samples, undergo neuroimaging procedures (MRI and EEG), and wear an actigraphy device for two weeks
Follow-up
Participants are monitored for safety and effectiveness after assessments
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
St. Joseph's Healthcare Hamilton
Lead Sponsor
Simon Fraser University
Collaborator
University of British Columbia
Collaborator
Unity Health Toronto
Collaborator
Centre for Addiction and Mental Health
Collaborator
Queen's University
Collaborator
University of Ottawa
Collaborator
University of Calgary
Collaborator
McGill University
Collaborator
Nova Scotia Health Authority
Collaborator