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Online Yoga vs. Behavioral Therapy for Depression

N/A
Recruiting
Led By Louisa Sylvia, PhD
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week: 0, 6, 12, 18, 24
Awards & highlights

Study Summary

This trial will compare online yoga to online therapy for treating depression.

Who is the study for?
Adults with depression (PHQ-9 score ≥10) who can read English or Spanish, live in NC, MA, MN, or RI and have a healthcare provider. Not for those with recent bone fractures/joint surgery, severe heart/lung disease, advised against exercise by a doctor, currently pregnant or engaged in yoga/psychotherapy recently.Check my eligibility
What is being tested?
This study compares an online group-based yoga program to individualized behavioral therapy (BA) for depression over 12 weeks. Participants will be randomly assigned to either the yoga or BA group and assessed at multiple points during and after treatment.See study design
What are the potential side effects?
Potential side effects are not specified but may include typical risks associated with physical activity like muscle strain for the yoga intervention. Behavioral Activation Therapy generally has minimal side effects but could include emotional discomfort.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week: 0, 6, 12, 18, 24
This trial's timeline: 3 weeks for screening, Varies for treatment, and week: 0, 6, 12, 18, 24 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Patient Health Questionnaire-9 (PHQ-9)
Secondary outcome measures
PROMIS-29 Anxiety Subscale
PROMIS-29 Sleep Subscale
World Health Organization-5 Well-Being Index (WHO-5)
Other outcome measures
PROMIS Anger
PROMIS-29 Pain Interference
PROMIS-29 Physical Functioning Subscale
+1 more

Trial Design

2Treatment groups
Active Control
Group I: Behavioral ActivationActive Control1 Intervention
The goal of Behavioral Activation Psychotherapy is to help people identify and (re)engage in meaningful and positive activities through psychoeducation, identification of values and associated activities, goal setting, problem-solving, and monitoring of goal completion. There will be a BA manual for therapists and training provided by study staff on the manual (e.g., asynchronous and synchronous training sessions). BA therapists will be community clinicians. BA will be provided individually via telehealth and will be billed to participant insurance. At the start of BA treatment, participants will be oriented to the time-limited nature of BA, with the expectation that they will attend 8 sessions over the course of 3 months.
Group II: Yoga-based InterventionActive Control1 Intervention
Yoga classes will be gentle and physically accessible for people who are naïve to yoga. Teachers will frequently guide participants to focus on their breathing and coordinate movements with breath. Teachers will offer variations on the postures and encourage participants to choose variations that provide some challenge but do not cause strain or pain. Classes will be 1 hour long and include a brief sitting meditation, warm-ups, standing postures, and a final resting meditation. All participants will be invited to attend a synchronous yoga class via a HIPAA-compliant videoconference option once per week during the first 3 months of the study. Classes will be offered at multiple times throughout the week.

Find a Location

Who is running the clinical trial?

Butler HospitalOTHER
129 Previous Clinical Trials
15,900 Total Patients Enrolled
31 Trials studying Depression
5,871 Patients Enrolled for Depression
Brown UniversityOTHER
456 Previous Clinical Trials
557,836 Total Patients Enrolled
29 Trials studying Depression
11,189 Patients Enrolled for Depression
Massachusetts General HospitalLead Sponsor
2,931 Previous Clinical Trials
13,197,927 Total Patients Enrolled
184 Trials studying Depression
29,038 Patients Enrolled for Depression

Media Library

Online- BA Clinical Trial Eligibility Overview. Trial Name: NCT05546697 — N/A
Depression Research Study Groups: Behavioral Activation, Yoga-based Intervention
Depression Clinical Trial 2023: Online- BA Highlights & Side Effects. Trial Name: NCT05546697 — N/A
Online- BA 2023 Treatment Timeline for Medical Study. Trial Name: NCT05546697 — N/A
Depression Patient Testimony for trial: Trial Name: NCT05546697 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there vacancies available for participants in this clinical trial?

"The data posted on clinicaltrials.gov reveals this trial is no longer in need of participants, as the initial posting date was January 1st 2023 and it was last updated on September 19th 2022. However, there are an abundance of other studies actively searching for volunteers at present with 1288 trials open to recruitment."

Answered by AI

Who else is applying?

What state do they live in?
Massachusetts
What site did they apply to?
Massachusetts General Hospital
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

I've struggled with depression for a few years without much reprieve from symptoms.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Expanding First-line Options for Depression and Matching Treatments to Patients: Hatha Yoga vs. Behavioral Therapy
Louisa Grandin Sylvia 2023. "Expanding First-line Options for Depression and Matching Treatments to Patients: Hatha Yoga vs. Behavioral Therapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05546697.
All > Depression Boston
~327 spots leftby May 2026
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