The current literature reviews the clinical characteristics of the autism spectrum and the diagnostic and conceptual status of Asperger syndrome, and highlights some key differences between the two disorders. The differential diagnostic implications of these findings are discussed. A multisystem view of autistic disorder is emphasized, in distinction to a simple distinction between high and low-functioning variants of Asperger syndrome. While the present paper is in part a research paper, it reflects clinicians' experiences with patients with the autism spectrum, and therefore might be helpful to clinicians and therapists in clinical practice.
The most often reported signs and symptoms of autism are social impairment, impaired communication skills, abnormal eating behaviours, restricted and stereotyped behaviours and interests. Autistic disorder is diagnosed by clinical assessments of symptoms. This involves the use of structured interviews, observational techniques and, where appropriate, psychophysiological testing or scanning.
Overall, 3.9 million individuals are estimated to have ASD in the United States. Furthermore, it is estimated that 11.1 million individuals are diagnosed with ASD for a lifetime.
There was no statistically significant difference in treatment between the two groups, so there is no need to highlight in this article the use of CBT, which is the most used method in both groups. The use of one treatment does not necessarily preclude the use of another.
According to our data, the effectiveness of different forms of treatment does not differ. However, the outcome is not always as good as the results at admission. However, it is not possible to predict if the treatment will eradicate the symptoms (for example the need for medications or surgery).
Individuals with autism may have abnormal genes influencing brain development and this may be the cause of the disorder. There is also some evidence that vitamin B12 deficiency may contribute. However, many factors are thought to be involved in the development of autism and new research shows that there is not just one factor that causes the disorder. Also, it has recently been determined the 'hot flush' is not due to an endocrine problem. Research suggests that women are more likely to develop Asperger's, and autistic children are more likely to be born prematurely, which makes its cause unclear. The use of Rett syndrome (mental retardation) to explain the causes of autism are discussed by David Amaral.
Epidiolex is commonly used in combination with other treatments in clinical trials. The majority of these trials are for autism spectrum disorders and are reported to reflect the overall clinical outcome of the combined therapy.
We believe that there are many factors causing autistic disorder and the primary cause is unknown. Some common hypotheses and their rationale include\n\n- a defective immune system predisposing individuals to infection,\n- genetic and hormonal problems, and\n- nutritional or physical problems.\n\nThe primary cause of AD is unknown but there are many hypotheses. Many believe that this disease is multifaceted and has many causes [e.g. genetics, neurological, psychosocial, vaccine-, or environment-related and others.]\n\n- The 'immune dysregulation hypothesis' is gaining favor with many researchers.
The current results support the view that a subgroup of individuals with autism spectrum disorders have a unique profile of the child's developmental and clinical picture that may merit consideration for treatment with this herbal remedy.
Most of the patients in this study had at least one clinical feature that put them at higher risk for disease progression. No patient had clinical features that made them ineligible for these clinical trials. Those patients who were able to complete the studies reported good results and those who did not complete the studies reported poorer results. This suggests that patients should be given a clinical trial before the decision to give medication is made.
Autism is not as dire as many believe. It can be manageable and most children and teenagers can be successfully treated early with a highly individualised program. However, some children and adults will continue to suffer from disabling cognitive difficulties, and social, behavioural and academic problems. [Power]