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Behavioral Intervention

Aerobic Exercise for Depression

N/A
Recruiting
Research Sponsored by The Royal's Institute of Mental Health Research
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Currently experiencing depression (MDD or PDD);
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, mid-intervention (6 weeks), post-intervention (12 weeks), 3-month follow-up, 6-month follow-up
Awards & highlights

Study Summary

This trial will compare the effects of moderate vs. high intensity aerobic exercise on depression, cognition, and brain function in young adults.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You are currently going through a period of depression.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, mid-intervention (6 weeks), post-intervention (12 weeks), 3-month follow-up, 6-month follow-up
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, mid-intervention (6 weeks), post-intervention (12 weeks), 3-month follow-up, 6-month follow-up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adherence to moderate & high intensity exercise regimens as prescribed
Changes in clinician-rated depression-related symptoms
Changes in self-reported depression-related symptoms
+2 more
Secondary outcome measures
Changes in cognitive function
Changes in daily functioning
Changes in electrocortical-indexed brain activity profiles
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Moderate IntensityExperimental Treatment1 Intervention
Aerobic exercise maintained for 30 minutes at 50-55% of each participant's individual heart rate reserve (HRRes).
Group II: High IntensityExperimental Treatment1 Intervention
Aerobic exercise maintained for 30 minutes at 80-85% of each participant's individual heart rate reserve (HRRes).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Aerobic Exercise
2013
Completed Early Phase 1
~1310

Find a Location

Who is running the clinical trial?

The Royal's Institute of Mental Health ResearchLead Sponsor
4 Previous Clinical Trials
1,110 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What ultimate goals are investigators hoping to accomplish with this trial?

"This clinical trial will span several checkpoints, including Baseline, Mid-Intervention (6 weeks), Post-Intervention (12 weeks), 3-month follow-up and 6 month follow up. The investigation's primary objective is to measure shifts in depression related symptoms as reviewed by clinicians. Secondary outcomes are changes to cognitive function evaluated with the NIH Cognitive Toolbox; a compilation of seven computerised tests designed to assess multiple intellectual capacities. This data will then be combined for analysis. Additionally, self mastery appraisals using Perlin/Schooler’s Mastery Scale - a 7 item questionnaire - along with neuroimaging indexed brain activity"

Answered by AI

Are there any limits on the number of participants enrolling in this experiment?

"Correct. According to the information stored on clinicaltrials.gov, this trial is actively seeking out 40 participants from a single medical centre. The study was initially posted on August 7th 2018 and has since been updated as recently as May 2nd 2022."

Answered by AI

To what demographic is this experiment open?

"This study is seeking around 40 individuals with depression aged between 16 and 24. Those who meet these requirements may be accepted in the trial."

Answered by AI

Is there an age requirement to be eligible for this medical trial?

"Based on the inclusion criteria, this study is open to individuals aged 16 to 24. There are 177 clinical trials that focus specifically on minors and 848 dedicated to those over 65 years old."

Answered by AI

Are there any open opportunities to participate in this research?

"Clinicaltrials.gov states that this experiment is currently searching for study participants, with the original posting taking place on August 7th 2018 and most recent edits occurring May 2nd 2022."

Answered by AI
~6 spots leftby Mar 2025