MI Paste for Denture Wearers
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you have taken antibiotics or antifungals in the past two months.
Is MI Paste safe for denture wearers?
The research does not provide specific safety data on MI Paste for denture wearers, but it highlights that some dental materials can cause allergic reactions, especially in people with previous allergies or burning mouth syndrome. It's important to consult with a healthcare provider to discuss any potential risks.12345
How does MI Paste differ from other treatments for denture wearers?
MI Paste is unique because it is specifically designed to remove denture plaque and has antimicrobial properties, effectively targeting microorganisms like streptococci and yeast. This makes it different from other denture-cleaning pastes, which may not have the same level of antimicrobial action or patient acceptance.678910
What is the purpose of this trial?
The purpose of this study is to determine if MI Paste affects the bacteria and fungus present within the mouth, as well as to determine if MI Paste increases denture comfort and retention. MI Paste is a water-based topical dental product that is available without a prescription. It is generally used to treat dental/tooth hypersensitivity (sensitive teeth) in patients and/or to help re-mineralize the tooth enamel in patients. Within this study, there is an off-label use for research subjects to apply above the upper denture.
Research Team
Robert Bowers, DDS
Principal Investigator
University of Iowa
Eligibility Criteria
This trial is for elderly individuals who wear removable dentures. Participants should be interested in testing whether a dental product, MI Paste, can improve the health of their mouth by affecting bacteria and fungus, as well as enhance denture comfort and fit.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants apply MI Paste under their removable upper denture for 14 days
Follow-up
Participants are monitored for changes in oral microbiome composition and denture comfort
Treatment Details
Interventions
- MI Paste
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Iowa
Lead Sponsor