MI Paste for Denture Wearers
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if MI Paste can reduce bacteria and fungus in the mouth and improve denture comfort and fit. MI Paste, a topical dental product, is typically used for sensitive teeth and strengthening tooth enamel. Participants will apply the paste above their upper dentures for seven days. Suitable candidates have well-fitting upper dentures and have not recently taken antibiotics or antifungals. As an unphased trial, this study allows participants to contribute to dental health research and potentially experience improved denture comfort.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you have taken antibiotics or antifungals in the past two months.
What prior data suggests that MI Paste is safe for denture wearers?
Research shows that MI Paste is generally safe to use. This dental product often helps with sensitive teeth and strengthens tooth enamel. Although specific safety information for people with dentures is lacking, it has been widely used for other dental issues without major concerns.
Some information suggests that MI Paste could cause an allergic skin reaction in rare cases, but these reactions are uncommon. The paste contains titanium dioxide, but it is mixed in a way that reduces any risk.
Overall, MI Paste is well-tolerated by most people, with only minor potential side effects. Notably, this product is available without a prescription, indicating a good safety record.12345Why are researchers excited about this trial?
Unlike traditional denture adhesives and creams that mainly focus on keeping dentures in place, MI Paste offers a unique approach by enhancing oral health through remineralization. It contains a special ingredient called Recaldent (CPP-ACP), which helps replenish lost minerals in the teeth and mouth, potentially reducing sensitivity and improving overall oral comfort for denture wearers. Researchers are excited about MI Paste because it not only addresses stability but also promotes healthier oral environments, which could lead to more comfortable denture use and improved oral health outcomes.
What evidence suggests that MI Paste might be an effective treatment for denture comfort and retention?
Research has shown that MI Paste, which participants in this trial will apply for 7 days, benefits people who wear dentures. It increases saliva production and balances the mouth's acidity, potentially lowering the risk of cavities for those with removable dentures. MI Paste also helps control bacteria and fungi in the mouth, which is important for maintaining cleanliness. Often used to treat sensitive teeth and strengthen tooth enamel, this product may offer additional benefits under dentures by boosting saliva, enhancing comfort, and improving fit.15678
Who Is on the Research Team?
Robert Bowers, DDS
Principal Investigator
University of Iowa
Are You a Good Fit for This Trial?
This trial is for elderly individuals who wear removable dentures. Participants should be interested in testing whether a dental product, MI Paste, can improve the health of their mouth by affecting bacteria and fungus, as well as enhance denture comfort and fit.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants apply MI Paste under their removable upper denture for 14 days
Follow-up
Participants are monitored for changes in oral microbiome composition and denture comfort
What Are the Treatments Tested in This Trial?
Interventions
- MI Paste
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Iowa
Lead Sponsor