← Back to Search

Cognitive Intervention with Leisure Activities for Cognitive Impairment

N/A
Waitlist Available
Led By Sylvie Belleville, PhD
Research Sponsored by Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Have a Montreal Cognitive Assessment (MoCA) total score of 20 and above
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre (within 12 weeks before intervention starts) + post-1 (within 8 weeks after the end of intervention) + post-2 (2 years from pre, +/- 3 months)
Awards & highlights

Study Summary

This trial will test a cognitive intervention meant to increase cognitive and brain reserve in people with subjective cognitive decline.

Who is the study for?
This trial is for individuals with subjective cognitive decline who are worried about their memory, have certain scores on memory and cognition tests, can commit to the full intervention plus follow-ups, and have internet at home. Excluded are those with recent major surgery or serious illness, substance abuse issues, no study partner, insufficient English/French proficiency in Toronto/Montreal respectively, or extensive music training.Check my eligibility
What is being tested?
The trial is testing a program that combines cognitive training sessions with engaging leisure activities like Spanish lessons or music appreciation (ENGAGE SPANISH/MUSIC) versus discovery-based learning (ENGAGE DISCOVERY). It's designed to see if these activities can boost brain function in people noticing early memory problems.See study design
What are the potential side effects?
Since this trial involves non-medical interventions such as cognitive exercises and leisure activities rather than drugs or medical procedures, traditional side effects are not expected. However, participants may experience fatigue or frustration.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My cognitive function score is 20 or higher.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre (within 12 weeks before intervention starts) + post-1 (within 8 weeks after the end of intervention) + post-2 (2 years from pre, +/- 3 months)
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre (within 12 weeks before intervention starts) + post-1 (within 8 weeks after the end of intervention) + post-2 (2 years from pre, +/- 3 months) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in episodic memory (composite score)
Secondary outcome measures
Changes in attention control (composite score)
Changes in brain function: Brain activation (for a subgroup of participants)
Changes in brain structure: Cortical Thickness (for a subgroup of participants)
+5 more
Other outcome measures
Transfer to everyday life (performance-based): Instrumental Activities of Daily Living
Transfer to everyday life (performance-based): Memory Strategies
Transfer to everyday life (self-reported): Activities of daily living
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ENGAGE SPANISH/MUSICExperimental Treatment1 Intervention
Cognitive strategies to improve attention and memory skills and application in selected leisure activities (music or Spanish lessons, and videogames) over 4 months.
Group II: ENGAGE DISCOVERYActive Control1 Intervention
Educational program about brain and healthy aging complemented by learning of new information with videogames, documentaries and group discussions over 4 months.

Find a Location

Who is running the clinical trial?

Centre de Recherche de l'Institut Universitaire de Geriatrie de MontrealLead Sponsor
22 Previous Clinical Trials
8,745 Total Patients Enrolled
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,336 Previous Clinical Trials
25,750,964 Total Patients Enrolled
Rotman Research Institute at BaycrestOTHER
10 Previous Clinical Trials
318 Total Patients Enrolled

Media Library

ENGAGE DISCOVERY Clinical Trial Eligibility Overview. Trial Name: NCT03271190 — N/A
Mild Cognitive Impairment Research Study Groups: ENGAGE SPANISH/MUSIC, ENGAGE DISCOVERY
Mild Cognitive Impairment Clinical Trial 2023: ENGAGE DISCOVERY Highlights & Side Effects. Trial Name: NCT03271190 — N/A
ENGAGE DISCOVERY 2023 Treatment Timeline for Medical Study. Trial Name: NCT03271190 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~19 spots leftby Mar 2025