Cognitive Intervention with Leisure Activities for Cognitive Impairment

Recruiting at 1 trial location

Overseen By Sylvie Belleville, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Disqualifiers: CNS disease, Stroke, Major surgery, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

144 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The team "Cognitive intervention, cognitive reserve and brain plasticity", Team 10, is part of the Canadian Consortium on Neurodegeneration in Aging (CCNA). The team's aim is to develop and test a multi-faceted intervention program meant to increase cognitive and brain reserve by providing cognitive stimulation through participation in cognitive training sessions and engaging leisure activities. This will be done with a partially randomized controlled double-blind preference trial with a comprehensive cohort design, in participants with subjective cognitive decline (SCD) recruited in Montreal and Toronto.

Who Is on the Research Team?

Sylvie Belleville, PhD

Principal Investigator

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Are You a Good Fit for This Trial?

This trial is for individuals with subjective cognitive decline who are worried about their memory, have certain scores on memory and cognition tests, can commit to the full intervention plus follow-ups, and have internet at home. Excluded are those with recent major surgery or serious illness, substance abuse issues, no study partner, insufficient English/French proficiency in Toronto/Montreal respectively, or extensive music training.

Inclusion Criteria

Possess sufficient visual and auditory acuity to undergo neuropsychological tests and the intervention

My cognitive function score is 20 or higher.

Have an internet connection at home

Exclusion Criteria

I have a disease or injury affecting my brain or spinal cord.

I have had surgery on my brain.

I have a serious health condition that could lead to death within a year.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

12 weeks

Intervention

Participants engage in cognitive strategies to improve attention and memory skills and apply them in selected leisure activities over 4 months.

4 months

Regular sessions (frequency not specified)

Follow-up

Participants are monitored for cognitive and psychological health outcomes, including brain structure and function, 2 years from the start of the study.

2 years

3 visits (PRE, POST-1, POST-2)

What Are the Treatments Tested in This Trial?

Interventions

• ENGAGE DISCOVERY
• ENGAGE SPANISH/MUSIC

Trial Overview The trial is testing a program that combines cognitive training sessions with engaging leisure activities like Spanish lessons or music appreciation (ENGAGE SPANISH/MUSIC) versus discovery-based learning (ENGAGE DISCOVERY). It's designed to see if these activities can boost brain function in people noticing early memory problems.

How Is the Trial Designed?

Group I: ENGAGE SPANISH/MUSIC Experimental Treatment 1 Intervention

Cognitive strategies to improve attention and memory skills and application in selected leisure activities (music or Spanish lessons, and videogames) over 4 months.

Group II: ENGAGE DISCOVERY Active Control 1 Intervention

Educational program about brain and healthy aging complemented by learning of new information with videogames, documentaries and group discussions over 4 months.

Who Is Running the Clinical Trial?

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Lead Sponsor

Trials

26

Recruited

9,500+

Canadian Institutes of Health Research (CIHR)

Collaborator

Trials

1,417

Recruited

26,550,000+

Rotman Research Institute at Baycrest

Collaborator

Trials

11

Recruited

460+