Digital Mind Body Intervention for Inflammatory Bowel Disease

(DMBI Trial)

Not yet recruiting at 1 trial location
RG
SB
SF
Overseen ByShalika Fnu
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Montefiore Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new digital mind-body intervention for individuals with inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis. The aim is to determine if a mobile app can reduce psychological stress and improve overall well-being, particularly for those experiencing stress and anxiety related to their IBD. Participants will either use the app or join a waitlist group that receives general health tips. The trial is especially suitable for Black, Hispanic, or Latino individuals who experience high stress levels and have IBD. As an unphased trial, it offers a unique opportunity to explore innovative methods for managing stress and enhancing quality of life for those with IBD.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this digital mind-body intervention is safe for people with inflammatory bowel disease?

Research has shown that digital mind-body techniques, such as mindfulness and cognitive-behavioral therapy (CBT), can aid individuals with inflammatory bowel disease (IBD). These methods are particularly beneficial for those with mood or anxiety issues.

The evidence for these digital methods is promising but still limited. Studies have not identified major safety concerns with these treatments. Participants in past studies did not report serious problems, and the treatments are generally well-tolerated.

Yoga-based mind-body techniques have also undergone study. They have reduced anxiety, depression, and stress in people with IBD. These results suggest that mind-body approaches are safe for most individuals.

Overall, digital mind-body techniques appear to be a safe option for managing psychological distress in IBD. However, more research is needed to confirm these findings across different groups.12345

Why are researchers excited about this trial?

Researchers are excited about the Digital Mind Body Intervention (DMBI) for inflammatory bowel disease (IBD) because it offers a completely novel approach by harnessing the power of digital technology to manage symptoms. Unlike traditional treatments that often rely on medication to reduce inflammation and immune response, DMBI uses a mobile application to promote mental and physical well-being through mind-body techniques, which could empower patients to manage their condition more actively. This digital approach is particularly appealing as it may minimize side effects associated with medication and provide a more personalized, accessible treatment option for IBD patients.

What evidence suggests that this Digital Mind Body Intervention is effective for inflammatory bowel disease?

Research shows that digital mind-body interventions (DMBIs) can help people with inflammatory bowel disease (IBD). For example, yoga-based programs significantly reduce anxiety, depression, and stress in IBD patients. Another study discovered that mindfulness-based cognitive therapy, which uses mindfulness to change thinking patterns, reduces fatigue in people with IBD. While strong evidence supports these digital approaches for improving mental health, more research is needed to confirm their effectiveness across diverse backgrounds. This trial will evaluate the Digital Mind Body Intervention, which participants may receive, to further explore its potential as a tool for managing both the mental and physical aspects of IBD.12346

Who Is on the Research Team?

RG

Ruby Greywoode, MD

Principal Investigator

Montefiore Medical Center

Are You a Good Fit for This Trial?

This trial is for Black and Hispanic individuals living with Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis. It aims to help those who may experience psychological distress due to their condition, especially if they face barriers like healthcare access or mental health stigma.

Inclusion Criteria

Ability to provide informed consent in English
Self-identify as Black/African American and/or Hispanic/Latino(a/x)
Elevated psychological distress: at least one T-score within 2.5 standard deviations above the mean on the NIH Toolbox Perceived Stress Scale or in the domains of either Anxiety or Depression on the NIH PROMIS-29.
See 1 more

Exclusion Criteria

Anxiety, depression, or perceived stress T-scores above 2.5 standard deviations above the mean
I have not had any recent suicidal thoughts, attempts, or psychiatric hospitalizations.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Development and Testing

Patient focus groups and semi-structured interviews are conducted to assess needs and barriers for DMBI acceptance and use. A functional DMBI app is developed and evaluated through iterative patient user testing.

Not specified

Pilot Study

An 8-week pilot of the refined DMBI intervention is conducted to assess feasibility and acceptability among Black and Hispanic patients with IBD.

8 weeks
Weekly interactions via the mobile app

Follow-up

Participants are monitored for safety and effectiveness after the pilot study.

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Digital Mind Body Intervention
Trial Overview The study tests a Digital Mind Body Intervention (DMBI) mobile app designed to manage the psychological aspects of IBD. The intervention focuses on mindfulness and coping strategies that could improve patients' quality of life by addressing the gut-brain interaction.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Digital Mind Body InterventionExperimental Treatment1 Intervention
Group II: Waitlist ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Montefiore Medical Center

Lead Sponsor

Trials
468
Recruited
599,000+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials
394
Recruited
404,000+

Citations

The Future of Telehealth‐Based Psychological and Mind ...The evidence to support using telehealth‐based psychological and mind–body interventions to support individuals with IBD is limited, but promising.
Meta-analysis of Yoga-based Mind-Body Interventions in ...Yoga-based mind-body interventions (YMBIs) significantly reduced anxiety, depression, and perceived stress in IBD patients, demonstrating their ...
Digital Mind Body Intervention Among Black and Hispanic ...The bidirectional effects between psychological distress and inflammatory bowel disease (IBD) activity mean that not only does increased IBD activity ...
Does Mind-Body Therapy for Inflammatory Bowel Disease ...In other recent research, mindfulness-based cognitive therapy (MBCT) led to reduced subjective fatigue in IBD (36% vs 10% in controls), and a ...
A Qualitative Study | Inflammatory Bowel Diseases | Oxford ...Although high-quality evidence suggests psychological improvement with certain digital behavioral interventions in IBD,13 feasibility and ...
Digital Mind Body Intervention for Inflammatory Bowel ...Participants are monitored for safety and effectiveness after the pilot study. ... Your Data Stays Your DataWe only share your information with the clinical ...
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