Precision 7 Contact Lenses for Contact Lens Comfort

Overseen By Chris Lievens, OD

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Southern College of Optometry

Must not be taking: Isotretinoin, Ocular medications

Disqualifiers: Presbyopia, Dry eye, Ocular allergies, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 week

40 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial focuses on testing how well individuals satisfied with their Acuvue Oasys contact lenses can transition to Precision 7 contact lenses. The main goal is to determine if these new lenses provide comfort and fit comparable to the old ones. It suits those who have worn Acuvue Oasys lenses for at least three months in the past year, have astigmatism (a common vision issue where the eye doesn't focus light evenly), and are satisfied with their current lenses. Participants should be prepared to try the new lenses daily and have a recent glasses prescription. As an unphased trial, this study offers a unique opportunity to explore new lens options and contribute to advancements in vision care.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are currently using isotretinoin-derivatives or ocular medications.

What prior data suggests that Precision 7 contact lenses are safe for contact lens wearers?

Research has shown that Precision 7 contact lenses are generally safe to use. One study found that users can wear these lenses for up to 6 nights and 7 days with few negative effects on the eyes, indicating that serious issues, such as eye infections, are rare. The lenses are designed to be comfortable and provide clear vision for up to 16 hours, suggesting that most people find them easy to wear. Overall, current data indicates that users tolerate these lenses well. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about Precision 7 contact lenses because they aim to enhance comfort for contact lens wearers, particularly those previously satisfied with Acuvue Oasys lenses. Unlike standard options that focus primarily on vision correction, Precision 7 lenses are designed with advanced materials that may better conform to the eye, potentially reducing irritation and dryness. This innovation could offer a more comfortable and satisfying wearing experience, making daily wear more pleasant for users.

What evidence suggests that Precision 7 contact lenses are effective for contact lens comfort?

Studies have shown that Precision 7 contact lenses provide up to 16 hours of comfort and clear vision, even after a week of use. The lenses have passed all safety and effectiveness tests, proving their safety for wear. Designed for weekly replacement, they remain fresh and comfortable. Overall, they offer excellent comfort and vision quality, making them an excellent choice for those considering a switch from other contact lenses. ^{1 2 5 6 7}

Who Is on the Research Team?

Chris Lievens

Principal Investigator

The Southern College of Optometry

Are You a Good Fit for This Trial?

This trial is for adults aged 18-40 who have worn Acuvue Oasys contact lenses for at least 3 months, have astigmatism between 0.75D to 2.50D in each eye, and are satisfied with their current lenses. Participants must be able to wear Precision 7 contact lenses daily for over 13 hours without overnight use and have a recent glasses prescription.

Inclusion Criteria

Astigmatism ranging from 0.75 D to 2.50 D in each eye

Participants must have worn AOA CLs for at least 3 months in the past year and currently wearing these CLs

Participants must be able to wear P7A CLs (astigmatism ≥0.75D OD/OS)

Exclusion Criteria

Have presbyopia and/or need a reading add as determined during their initial manifest refraction

Have worn P7A in the past

Are past rigid CL wearers

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants are refitted from Acuvue Oasys for Astigmatism contact lenses to PRECISION7 for Astigmatism contact lenses

1 week

1 visit (in-person)

Follow-up

Participants are monitored for satisfaction, comfort, and vision quality after refitting

1 week

What Are the Treatments Tested in This Trial?

Interventions

• Precision 7 contact lenses

Trial Overview

The study aims to see if people happy with their Acuvue Oasys contacts can switch successfully to Precision 7 contact lenses designed for astigmatism. It involves regular wearing of the new P7A lenses during waking hours over a set period.

How Is the Trial Designed?

Group I: PRECISION7 Experimental Treatment 1 Intervention

Determine the likelihood of successfully refitting a satisfied Acuvue Oaysis Contact Lens wearers into P7A CLs.

Who Is Running the Clinical Trial?

Southern College of Optometry

Lead Sponsor

Trials

8

Recruited

390+

Eminent Ophthalmic Services

Collaborator

Published Research Related to This Trial

In a study of 74 children aged 8 to 12, MiSight contact lenses were found to be a safe option for myopia correction, with no serious or significant adverse events reported over a 2-year period.

While there were some nonsignificant adverse events and a few discontinuations in the MiSight group, the overall safety profile was comparable to that of distance single-vision spectacles, indicating that both options are effective for managing myopia.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

MiSight Assessment Study Spain: Adverse Events, Tear Film Osmolarity, and Discontinuations. Ruiz-Pomeda, A., Pérez-Sánchez, B., Prieto-Garrido, FL., et al.[2018]

Citations

1.

accessdata.fda.gov

accessdata.fda.gov/cdrh_docs/pdf22/P220007B.pdf

Summary of Safety and Effectiveness Data (SSED)

All test results met the pre-established acceptance criteria. The testing performed on the Precision7™ (serafilcon A) extended wear soft contact ...

2.

withpower.com

withpower.com/trial/phase-contact-lens-comfort-3-2025-dc36f

Precision 7 Contact Lenses for Contact Lens Comfort

The safety of contact lenses, including those similar to Precision 7, has been studied in terms of comfort and adverse events (unwanted effects).

3.

myalcon.com

myalcon.com/professional/contact-lenses/weekly/precision7/

Precision7® Parameters and Technical Specifications - MyAlcon

The new 1-week replacement lenses that offer 16 hours of outstanding comfort and precise vision, even on day 7.

4.

investor.alcon.com

investor.alcon.com/news-and-events/press-releases/news-details/2024/Alcon-Debuts-Groundbreaking-PRECISION7-a-One-Week-Replacement-Contact-Lens-to-Start-and-End-Every-Week-Fresh/default.aspx

Alcon Debuts Groundbreaking PRECISION7, a One-Week ...

PRECISION7, a new one-week replacement lens, provides 16 hours of outstanding comfort and precise vision, even on day 7 1; Features world's ...

5.

pmc.ncbi.nlm.nih.gov

pmc.ncbi.nlm.nih.gov/articles/PMC10442754/

Clinical Performance and Patient Satisfaction of Hybrid ...

The overall satisfaction score was moderate to good and the disadvantages were low comfort compared to soft CL, difficulty with insertion and ...

6.

fda.gov

fda.gov/medical-devices/recently-approved-devices/precision7-precision7-astigmatism-precision7-multifocal-precision7-multifocal-toric-serafilcon

Precision7 Soft Contact Lenses - P220007

The study also showed that this lens can be worn for up to 6 nights/7 days with limited negative effects on the eyes (ocular adverse events ...

7.

precisionlab.com

precisionlab.com/wp-content/uploads/2024/02/Elimino-SDS.pdf

SAFETY DATA SHEET PRECISION LABORATORIES, LLC

Contact lenses should not be worn when working with chemicals. Skin Protection: Wear chemically impervious gloves, long-sleeved shirt, pants ...