Community Program for Colorectal Cancer Prevention

Overseen By Bianca Rosales

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Southern California

Disqualifiers: Cognitive deficit, Psychiatric impairment, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 4

140 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate how effectively trained community specialists can enhance communication about preventing colorectal cancer and genetic testing in Hispanic/Latino communities. The focus is on educating these communities to reduce cancer risks through a better understanding of genetic factors. Participants will either receive existing information on the topic or attend a training session led by Community Genetic Navigation Specialists (CoGENES, part of the Community Genetic Navigation Specialists Program). Individuals who identify as Hispanic/Latino, reside in Los Angeles County, and speak English or Spanish are well-suited for this trial. As an unphased trial, this study provides a unique opportunity to contribute to community health education and cancer prevention efforts.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It focuses on community engagement and education rather than medical treatment.

What prior data suggests that the Community Genetic Navigation Specialists Program is safe?

Research has shown that the Community Genetic Navigation Specialists (CoGENES) Program improves communication about preventing colorectal cancer and understanding genetic testing. This program educates Hispanic/Latino/a/x communities on these topics.

Regarding safety, the program is educational rather than medical. It involves no medications or medical procedures, so there are no physical side effects. Participants receive training and information, which is generally safe. The goal is to increase knowledge and help individuals make informed health decisions.

For those considering joining the program, the primary "side effect" is gaining more knowledge about preventing colorectal cancer and genetic testing. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Community Genetic Navigation Specialists Program (CoGENES) because it offers a fresh approach to colorectal cancer prevention by focusing on education and empowerment. Unlike standard options that typically involve direct medical interventions like screenings or genetic testing, CoGENES emphasizes personalized training sessions to boost understanding and proactive management of cancer risks. This program stands out by providing direct, individualized guidance through community specialists, which could lead to better-informed decisions and potentially earlier detection and prevention of colorectal cancer.

What evidence suggests that the Community Genetic Navigation Specialists Program is effective for improving communication on colorectal cancer prevention?

Research has shown that the Community Genetic Navigation Specialists (CoGENES) Program, available to participants in this trial, holds promise for improving communication about colorectal cancer prevention and genetic testing in Hispanic/Latino communities. Studies have found that programs like CoGENES can boost participants' confidence in taking action and enhance their knowledge. Understanding inherited genetic mutations significantly impacts treatment choices and outcomes. By focusing on cultural values and addressing the challenges these communities face, CoGENES aims to reduce cancer disparities. It trains community health workers to engage and educate effectively, potentially leading to increased cancer screenings and genetic testing. ^{1 2 6 7 8}

Who Is on the Research Team?

Mariana C Stern, PhD

Principal Investigator

University of Southern California

Are You a Good Fit for This Trial?

This trial is for Hispanic/Latino/a/x individuals focused on improving communication about colorectal cancer prevention and genetic testing. It aims to educate and engage communities considering cultural values, literacy, barriers, beliefs, attitudes, and language.

Inclusion Criteria

I am 18 years old or older.

I can read, write, and speak in English or Spanish.

Resides in Los Angeles County

Exclusion Criteria

Any person unable to read and write Spanish or English

Resides outside of Los Angeles County

Any person who considers themselves a community health educator or 'promotor/a de salud' and/or has taken in the past three years training on colorectal cancer and/or cancer genetics

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive either a packet of information materials or a CoGENES training session

6-10 weeks

1 visit (in-person or virtual)

Follow-up

Participants are monitored for changes in knowledge and intentions regarding colorectal cancer prevention and genetic testing

12 months

3 visits (in-person or virtual) at 8 weeks, 6 months, and 12 months

What Are the Treatments Tested in This Trial?

Interventions

• Community Genetic Navigation Specialists Program

Trial Overview The trial tests the effectiveness of a program where trained specialists (CoGENES) provide education on colorectal cancer prevention and genetic testing within Hispanic/Latino communities to reduce disparities in cancer care.

How Is the Trial Designed?

Group I: Group 2 (CoGENES) Experimental Treatment 2 Interventions

Participants receive a CoGENES training session over 45-60 minutes.

Group II: Group 1 (usual care) Active Control 2 Interventions

Participants receive a packet of existing information materials about colorectal cancer prevention, screening, and genetic testing to review at their own pace over 6-10 weeks. Participants may optionally receive a CoGENES training session within 2 weeks post-intervention.

Who Is Running the Clinical Trial?

University of Southern California

Lead Sponsor

Trials

956

Recruited

1,609,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07229443

Study Details | NCT07229443 | Community Genetic ... This clinical trial evaluates the effectiveness of trained community engagement specialists for improving communication on colorectal cancer ...

2. aacrjournals.org aacrjournals.org/cancerres/article/84/6_Supplement/6131/740283/Abstract-6131-Increasing-self-efficacy-self

Abstract 6131: Increasing self efficacy, self confidence, and ... The Community Genetic Navigation Specialists (CoGENES) train-the-trainer program created a workforce of community health workers (CHWs) to ...

3. precisionmedicineonline.com precisionmedicineonline.com/precision-oncology/usc-center-testing-efficacy-colorectal-cancer-genetic-risk-education-hispanic

USC Center Testing Efficacy of Colorectal Cancer, Genetic ... The surveys will include questions that gauge the participants' knowledge and if they have or plan to get screened for colorectal cancer.

4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10185972/

Implementation of a Population-Based Cancer Family ... Of these, 47 (35%) were associated with Lynch syndrome while notably, 70 (53%) were not associated with hereditary colorectal cancer.

5. sciencedirect.com sciencedirect.com/science/article/abs/pii/S1551714422000611

Patient navigation for hereditary colorectal cancer Our pragmatic RCT design will provide real-world data on the potential for patient navigation to address longstanding care gaps in preventive genomic medicine.

6. ebccp.cancercontrol.cancer.gov ebccp.cancercontrol.cancer.gov/programDetails.do?programId=24393369

Family CARE (Colorectal Cancer Awareness and Risk ... Program Highlights. Purpose: Designed to promote colorectal cancer (CRC) screening among individuals with familial CRC risk (2014).

7. clinicaltrials.gov clinicaltrials.gov/study/NCT07228000

Bundled Cancer Screening and Genetic Services Navigation Colorectal cancer screening will be determined through electronic health records abstraction. Documentation of screening includes the test (FIT, ...

8. cinj.org cinj.org/outreach/community-projects-and-other-programming

Community Projects and Other Programming Rutgers Cancer Institute is offering a free six-week virtual program on cancer prevention and screening for community health workers.