xBar System for Colorectal Cancer

(ASSURE Trial)

Not yet recruiting at 2 trial locations
IF
RS
Overseen ByRuth Stone
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Exero Medical Ltd.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Purpose: To evaluate the effect of xBar system utilization on clinical outcomes during recovery following colorectal surgery.

Are You a Good Fit for This Trial?

This trial is for adults over 21 who are scheduled for elective low anterior resection due to colorectal cancer. Participants must have an expected anastomosis within 10 cm from the anal verge and agree to use a drain during surgery. They should be willing to follow study procedures and provide informed consent.

Inclusion Criteria

I am part of an interventional study group.
I am part of a historical cohort study.
My surgery or tumor is within 10cm of the anal opening and all records are available for 12 months or until stoma reversal.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Placement of the xBar system during elective low anterior resection surgery and continuous monitoring until drain removal

3 days
Continuous monitoring during hospital stay

Follow-up

Participants are monitored for safety and effectiveness after treatment, including evaluation of xBar's performance and stoma-free status

12 months
Follow-up assessments at 30 days, 90 days, 6 months, and 12 months

Long-term follow-up

Monitoring for any unexpected serious adverse device events and health resource utilization

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • xBar™ System

Trial Overview

The xBar™ System is being tested in this trial, which aims to see if it improves clinical outcomes after colorectal surgery. The study will compare results from patients using the system with historical data of those who did not.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Interventional CohortExperimental Treatment1 Intervention
Group II: Historical Control CohortActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Exero Medical Ltd.

Lead Sponsor

Trials
2
Recruited
200+