160 Participants Needed

A Study of the Possible Effects of Medication on Young Onset Colorectal Cancer (YOCRC)

AC
DK
Overseen ByDavid Kelsen, MD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Memorial Sloan Kettering Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will collect biospecimens (including blood, tissue, and stool samples) and health information to create a database-a type of collection of information-for better understanding young onset colorectal cancer (YOCRC). The study will include both people with YOCRC and healthy people.

Who Is on the Research Team?

AC

Andrea Cercek, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Are You a Good Fit for This Trial?

Inclusion Criteria

Planned CRC resection biopsy , or colonoscopy (only patients providing tissue sample)
Enrollment in IRB# 20-315, Young Onset Gastrointestinal Cancer Prospective Registry (Andrea Cercek, PI)
Scheduled for standard-of-care colonoscopy at MSK
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Sample Collection

Collection of biospecimens including blood, tissue, and stool samples from participants

3 years
Visits as needed for sample collection

Genomic Analysis

Perform whole exome sequencing, MSK-IMPACT DNA-methylation, and RNA assays of normal colonic mucosa and tumor

3 years

Follow-up

Participants are monitored for safety and effectiveness after sample collection and analysis

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • None

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+

Shaare Zedek Medical Center

Collaborator

Trials
213
Recruited
53,600+

Technion, Israel Institute of Technology

Collaborator

Trials
70
Recruited
117,000+
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