Web-Based Genetic Education for BRCA Mutation Carriers
What You Need to Know Before You Apply
What is the purpose of this trial?
The primary goal of this research is to test a web-based genetic education intervention that is designed to educate men and women from hereditary cancer families about the personal relevance of genetic testing in order to help them male decisions about whether to pursue genetic testing. We will test this intervention against standard care for men and women from hereditary cancer families. The web-based educational intervention includes all of the information typically covered during genetic counseling. As a result, after completing the education intervention, participants can proceed directly to a brief telephone call with a genetic counselor followed by testing if they choose. A baseline survey will be administered prior to randomization and then follow-up surveys will be administered at 1-month and 6-months post-randomization. Primary outcomes will be completion of genetic counseling, uptake of genetic testing, genetic test results and quality of life.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is web-based genetic education for BRCA mutation carriers safe?
The research indicates that web-based and telephone genetic counseling methods, like DNA-direct, are generally safe and do not increase distress among participants. Participants reported satisfaction and lower distress levels compared to traditional face-to-face counseling, suggesting these methods are safe for use in humans.12345
How does the Web + Streamlined Telephone Genetic Counseling treatment differ from other treatments for BRCA mutation carriers?
This treatment is unique because it combines web-based education with streamlined telephone counseling, making genetic counseling more accessible and convenient for BRCA mutation carriers. It allows patients to learn at their own pace online while still providing the opportunity for personalized support through phone counseling, which can help address individual concerns and enhance understanding.678910
What data supports the effectiveness of the treatment Web + Streamlined Telephone Genetic Counseling for BRCA Mutation Carriers?
Research shows that many breast cancer patients prefer receiving genetic counseling through digital and telephone methods rather than face-to-face meetings, with high satisfaction and reduced distress. Additionally, tailored web-based information can improve patients' knowledge and expectations, suggesting that web-based education combined with telephone counseling could be effective for BRCA mutation carriers.1231112
Who Is on the Research Team?
Marc D Schwartz, PhD
Principal Investigator
Georgetown University
Are You a Good Fit for This Trial?
This trial is for men and women who have a close relative with a BRCA1 or BRCA2 mutation, indicating they might be at risk for hereditary cancer. They should not have metastatic cancer themselves, no prior genetic testing for these mutations, and must understand English to give informed consent.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Eligible participants complete a baseline survey via telephone or electronically
Randomization
Participants are randomized to either the W+T intervention or usual care
Intervention
W+T participants receive web-based education and a streamlined telephone genetic information session
Follow-up
Participants are monitored for uptake of genetic counseling and testing, and psychosocial outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Web + Streamlined Telephone Genetic Counseling
Find a Clinic Near You
Who Is Running the Clinical Trial?
Georgetown University
Lead Sponsor
George Washington University
Collaborator