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Cold vs Hot Snare EMR for Colonic Polyps (LPS-II Trial)
LPS-II Trial Summary
This trial is testing two different approaches to endoscopic mucosal resection (EMR) of large colorectal polyps. One approach uses electrocautery ("hot" snare EMR), and the other doesn't ("cold" snare EMR). Half of the patients will have their polyps removed using Eleview as the submucosal injection agent, and the other half will have their polyps removed using placebo (normal saline with methylene blue) as the submucosal injection agent.
LPS-II Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowLPS-II Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.LPS-II Trial Design
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Who is running the clinical trial?
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- I have inflammatory bowel disease.I am 18 or older and eligible for a colonoscopy without any exclusion criteria.I have ulcerated lesions or confirmed adenocarcinoma.I am undergoing an emergency colonoscopy.My overall health is poor.You are pregnant.My cancer is suspected to be deep within the lining of an organ.I have a large colorectal polyp that is not on a stalk.
- Group 1: Cold snare & Eleview injection
- Group 2: Hot snare & Placebo injection
- Group 3: Hot snare & Eleview injection
- Group 4: Cold Snare & Placebo injection
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are any new participants being welcomed into this trial?
"According to clinicaltrials.gov, the trial is in its active recruitment period; it was originally posted on October 1st 2019 and recently updated on May 28th 2021."
How many participants are allocated to this research endeavor?
"Affirmative. Per the clinicaltrials.gov information, this trial is currently in search of participants and was posted on October 1st 2019 with an update occurring on May 28th 2021. A total of 870 patients are being sought from a single site for enrolment."
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