Spatial Memory Training for Mild Cognitive Impairment
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether a 3-month spatial memory training program can improve memory and brain health in individuals with mild cognitive impairment (MCI). MCI involves noticeable memory problems, yet individuals can still function independently. The study focuses on the hippocampus, a brain region associated with memory, which may help prevent Alzheimer's disease. Individuals diagnosed with MCI who speak English or French might be suitable candidates for this trial. As an unphased trial, it offers participants the chance to contribute to groundbreaking research that could enhance understanding and treatment of memory issues.
Will I have to stop taking my current medications?
The trial requires that you have been on antidepressant, anti-anxiety, cholesterol, or hypertension medications for at least 3 months before joining. If you are taking medications for sleep problems, codeine, or antipsychotics, you cannot participate. The protocol does not specify other medication restrictions.
What prior data suggests that this spatial memory training is safe for individuals with mild cognitive impairment?
Research has shown that spatial memory training is generally safe for people with mild cognitive impairment (MCI). In past studies, participants reported no major side effects from this type of training. A review of treatments for MCI found improvements in thinking skills without significant problems. Another study on virtual reality-based spatial memory training also found it safe, with participants experiencing memory benefits without harmful side effects. This suggests that spatial memory training is a safe choice for those seeking to enhance memory and thinking abilities.12345
Why are researchers excited about this trial?
Researchers are excited about Spatial Memory Training for mild cognitive impairment because it focuses on enhancing cognitive function through a non-pharmacological approach. Unlike traditional treatments that often involve medication to manage symptoms, this training program aims to directly improve spatial memory skills, potentially offering a more direct method of addressing memory issues. By engaging patients in exercises designed to boost their spatial awareness and memory, there's hope for a safer, side-effect-free option that could complement or even replace drug-based therapies.
What evidence suggests that spatial memory training is effective for mild cognitive impairment?
Research has shown that training focused on spatial memory can improve memory and thinking skills in people with mild cognitive impairment (MCI). In this trial, participants will receive Spatial Memory Training as part of the Spatial Memory Intervention Program (SMIP). One study found that this type of training led to better overall thinking abilities and improved self-assessments. Another study discovered that cognitive training could slow memory decline over five years in people with MCI. Additionally, computer-based cognitive exercises have boosted both verbal and visual memory in those with MCI. These findings suggest that spatial memory training might help maintain and even enhance memory skills in people at risk of developing dementia.23567
Who Is on the Research Team?
Véronique Bohbot, Ph.D.
Principal Investigator
Douglas Mental Health University Institute
Are You a Good Fit for This Trial?
This trial is for people aged 55 or older who speak English or French and have been diagnosed with Mild Cognitive Impairment (MCI). It's not specified who can't join, but typically those with other serious health issues might be excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a 12-week spatial memory intervention program or an active control condition
Follow-up
Participants are monitored for changes in cognitive and memory performance post-treatment
What Are the Treatments Tested in This Trial?
Interventions
- Spatial Memory Training
Find a Clinic Near You
Who Is Running the Clinical Trial?
Douglas Mental Health University Institute
Lead Sponsor
Canadian Institutes of Health Research (CIHR)
Collaborator