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Repetitive Transcranial Magnetic Stimulation for Mild Cognitive Impairment
Study Summary
This trial will use a personalized, non-invasive brain stimulation protocol to prevent cognitive decline in patients with mild cognitive impairment (MCI) and cognitively normal individuals at high risk of developing Alzheimer's disease (AD).
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You must be able to speak English.You have not participated in another research study that involves receiving treatment within the past 6 months.You have difficulty with thinking and memory as shown by certain tests, such as the MMSE or MoCA, with scores between 24-27 or 18-26, respectively. Or, you have a Clinical Dementia Rating Scale score of 0.5.I can attend a daily session every weekday for 4 weeks.You have noticed problems with your memory or thinking, but you can still do things on your own without help. You do not have dementia.You have mild problems with your memory and thinking abilities.I am between 50 and 80 years old.You use your right hand dominantly.
- Group 1: Sham TBS
- Group 2: Excitatory TBS
- Group 3: Inhibitory TBS
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there still opportunities to participate in this experiment?
"Indeed, the data hosted on clinicaltrials.gov indicates that this medical trial is still enrolling candidates. It was initially uploaded to the database in October of 2020 and has since been updated on July 13th 2022. Currently, 60 patients need to be enrolled from one single location for a successful completion of the study goals."
What criteria must individuals meet in order to participate in this research project?
"This research seeks 60 people aged 50 to 80 with mild cognitive impairment. To qualify, they must have a self- or informant-reported complaint of decreased cognition; the capability to execute activities independently; be absent from any signs of dementia; show scores between 24 and 27 on the Mini-Mental State Exam (MMSE), 18 and 26 on Montreal Cognitive Assessment (MoCA) or 0.5 on Clinical Dementia Rating Scale score; know English language fluently; commit themselves for four weeks starting Monday through Friday daily sessions consecutively within six months prior enrolment in another interventional study, as well as being right handed."
Does this experiment allow for elderly individuals to participate?
"According to the participant requirements, individuals that are at least 50 years of age and not more than 80 may join this medical trial."
What is the aggregate number of participants enrolled in this experiment?
"Affirmative. Clinicaltrials.gov has data that supports this medical study's active recruitment phase, which began on October 21st 2020 and was most recently updated on July 13th 2022. Sixty individuals are sought from one site to partake in the trial."
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