Proton Pump Inhibitors for Acid Reflux
Trial Summary
What is the purpose of this trial?
The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority.This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.
Eligibility Criteria
This trial is for healthcare providers at UCLA Health who prescribe proton pump inhibitors (PPIs) for conditions like acid reflux. The study aims to optimize PPI prescribing practices within the Electronic Health Record system.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Evaluation of new variations of PPI order panels within the EHR system to optimize prescribing workflows
Follow-up
Participants are monitored for safety and effectiveness after intervention, focusing on prescription discontinuations and GI bleeding hospitalizations
Treatment Details
Interventions
- Proton Pump Inhibitors
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Who Is Running the Clinical Trial?
University of California, Los Angeles
Lead Sponsor
National Institute on Aging (NIA)
Collaborator