Cardiac rehabilitation - high intensity interval training (HIIT) for Cardiovascular Disease
Mayo Clinic in Rochester, Rochester, MN
Cardiac rehabilitation - high intensity interval training (HIIT) +3 moreN/ARecruitingLed by Bruce D Johnson, PhDResearch Sponsored by Mayo ClinicEligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Never been diagnosed with cardiovascular disease or coronary artery disease.
Current body mass index < 30kg/m2
Must not have
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Upbaseline and follow-up at 3-months
Awards & highlights
Study Summary
This trial will help researchers understand how cardiovascular disease affects brain blood flow and cognition, as well as whether exercise can improve brain blood flow and cognition.
Eligibility Criteria
Inclusion Criteria
You will be eligible if you check “Yes” for the criteria belowSelect...
You have never been diagnosed with heart disease or blockages in your heart's blood vessels.
Select...
Your current body weight is within a healthy range for your height.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and follow-up at 3-months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and follow-up at 3-months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cerebral blood flow regulation (as cerebrovascular reactivity)
Secondary outcome measures
Cognitive function
Other outcome measures
Cerebral blood flow regulation (as autoregulation)
Cerebral blood flow regulation (as neurovascular coupling)
Cerebral blood flow regulation to exercise
+2 moreTrial Design
5Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Cardiac rehabilitation - observationalExperimental Treatment1 Intervention
This observational group will include patients who are completing an exercise-based cardiac rehabilitation program in line with standard care but are not part of the randomized exercise protocol groups (HIIT or MICT). Participants in this group will be combined with HIIT and MICT (as exercise-based cardiac rehabilitation group) for Aims 1b and 2b.
Group II: Cardiac rehabilitation - High intensity interval training (HIIT)Experimental Treatment1 Intervention
Patients attending cardiac rehabilitation randomized to HIIT.
Group III: Cardiac rehabilitation - Moderate intensity continuous training (MICT)Active Control1 Intervention
Patients attending cardiac rehabilitation randomized to MICT.
Group IV: Healthy control groupActive Control1 Intervention
Healthy age-matched adults without cardiovascular disease, who will complete baseline assessments only. No intervention period.
Group V: Cardiac rehabilitation - controlPlacebo Group1 Intervention
The control group (12 week period) will include participants who have declined cardiac rehabilitation.
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Who is running the clinical trial?
Mayo ClinicLead Sponsor
3,048 Previous Clinical Trials
3,484,648 Total Patients Enrolled
Bruce D Johnson, PhDPrincipal Investigator
Mayo Clinic1 Previous Clinical Trials
80 Total Patients Enrolled
Media Library
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the total patient population of this clinical trial?
"Affirmative, per the information on clinicaltrials.gov this clinical trial is actively seeking participants. Initially posted on September 2nd 2021 and last modified on September 13th 2022, 87 people are sought after at a single site for recruitment purposes."
Answered by AI
Is there still availability for participants in this experiment?
"According to the data available on clinicaltrials.gov, this trial is currently recruiting patients and has been open for applications since September 2nd 2021 with updates logged as recently as 13th of September 2022."
Answered by AI