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Patients with stable CAD or acute coronary syndromes undergoing invasive coronary angiography for Cardiovascular Disease

N/A

Waitlist Available

Led By Guillermo J Tearney, MD, PhD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patient eligible for PCI

Patients must be over the age of 18

Timeline

Screening 3 weeks

Treatment Varies

Follow Up data will be analyzed within 1 year after the procedure.

Awards & highlights

Study Summary

This trial aims to use imaging techniques to study patients undergoing coronary angiography for heart conditions. They will be imaged with two different methods, OCT-NIRAF and CCTA, to see if the

Who is the study for?

This trial is for individuals undergoing coronary angiography due to stable or acute coronary disease and who are candidates for a procedure called PCI. Specific details about who can join or reasons why someone might not be eligible are not provided.Check my eligibility

What is being tested?

The study is testing OCT-NIRAF imaging during heart procedures to see if the level of NIRAF signal in arteries correlates with how severe the artery disease is, and if it can predict worsening of the condition over time.See study design

What are the potential side effects?

Potential side effects are not explicitly mentioned, but as with any imaging technique used during cardiac procedures, there may be risks associated with contrast use, radiation exposure from CCTA, and complications related to catheter insertion.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am eligible for a brain radiation procedure.

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I am over 18 years old.

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I have stable or acute heart issues and am getting a heart artery exam at MGH.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ data will be analyzed within 1 year after the procedure.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~data will be analyzed within 1 year after the procedure.

This trial's timeline: 3 weeks for screening, Varies for treatment, and data will be analyzed within 1 year after the procedure. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Plaque progression estimate using OCT-NIRAF

Plaque size estimation using OCT-NIRAF

Trial Design

1Treatment groups

Experimental Treatment

Group I: Patients with stable CAD or acute coronary syndromes undergoing invasive coronary angiographyExperimental Treatment1 Intervention

Patients referred to the Cardiology Division of the Massachusetts General Hospital, undergoing coronary angiography for stable or acute coronary disease and eligible for percutaneous coronary intervention (PCI) will be eligible for the study.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,936 Previous Clinical Trials

13,198,681 Total Patients Enrolled

Guillermo J Tearney, MD, PhDPrincipal InvestigatorMassachusetts General Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment of participants ongoing for this study?

"As per clinicaltrials.gov, the current research endeavor is not in pursuit of additional participants. Initially shared on April 30th, 2024 and last revised on April 16th, 2024; prospective applicants are no longer being sought for this particular investigation. Nonetheless, it's noteworthy that there exist a substantial number of 995 ongoing trials actively enrolling patients at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Study to Determine the Clinical Significance of Intravascular OCT-NIRAF

Guillermo Tearney 2024. "Study to Determine the Clinical Significance of Intravascular OCT-NIRAF". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06374498.

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